Dferol 50 Capsules (Soft Gelatin) with composition of Cholecalciferol (Vit. D3) used for:
- Osteoporosis
- Hypoparathyroidism
- Rickets
- Osteomalacia
- Vitamin D Deficiency
- Pseudohypoparathyroidism
- Familial hypophosphatemia
Dosage of Dferol 50
Adult Dose
Oral /IM: Nutritional deficiency Colecalciferol (Vitamin D3) recommended 5-10 mcg or 1-2ml (200-400 IU)/day Osteoporosis Prophylaxis and treatment >50 years: 800-1000 IU (20-25 mcg) PO once daily with calcium supplements. May also be given via IM inj. Hypoparathyroidism 50,000-200,000 IU (0.625-5 mg) PO once daily with calcium supplements. May also be given via IM inj.
Child Dose
Nutritional Supplementation RDA 0-12 months: 400 IU (10 mcg) PO once daily 1-18 years: 600 IU (15 mcg) PO once daily Vitamin D-Resistant Rickets 12,000-500,000 IU (0.3-12.5 mg) PO once daily Familial Hypophosphatemia 40,000-80,000 IU (1-2 mg) PO once daily with phosphate supplements; may be reduced after stage of growth is complete.
Contra Indications of Dferol 50
All disorders linked to hypercalcemia contraindicated with colecalciferol. Additionally, it should not used in patients who have a history of hypersensitivity to either the excipients or Colecalciferol (or medications in the same class). In cases where vitamin D toxicity is apparent, colecalciferol is contraindicated.
Precautions of Dferol 50
Consider using vitamin D supplements with caution if you have any of the following conditions:
High calcium or phosphorus levels in the blood
Heart issues
kidney illness
Supplementing with sufficient levels of calcium and magnesium is necessary when taking vitamin D. The body stimulates the parathyroid gland, which generates PTH, when the calcium level is low (as a result of inadequate vitamin D and calcium consumption) (parathyroid hormone). The creation of vitamin D hormone is sped up by this hormone, which also aids in the evacuation of calcium from the bones for use in more crucial processes like balancing body acidity.
Drug passes into breast milk during lactation; use with caution.
Interactions
increased risk of hypercalcaemia if administered with calcium or phosphate, thiazide diuretics, or both. Antiepileptic medications, such as carbamazepine, phenobarbitone, phenytoin, and primidone, may result in a greater need for vitamin D. Vitamin D effectiveness may be lowered by rifampicin and isoniazid. The effects of vitamin D may be counteracted by corticosteroids. any cardiac glycoside, such as digoxin. reduced absorption when combined with orlistat, mineral oil, cholestyramine, and colestipol. Ketoconazole.
Adverse Effects of Dferol 50
Cholecalciferol (Vit. D3) adverse effects: In general, nutritional supplements thought to be safe and well-tolerated. A few adverse effects, such as hypercalcaemia syndrome or calcium intoxication (depending on the degree and duration of hypercalcaemia), can occasionally develop with the use of colecaciferol, along with anorexia, headaches, dry mouth, nausea, vomiting, abdominal discomfort or stomach aches, and constipation.
Dferol 50 price in UAE
20 AED
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