GORDEX 40mg price in UAE

Overview

Welcome to Dwaey, specifically on GORDEX 40mg Capsules (Hard Gelatin) page.
This medicine contains an important and useful components, as it consists of Esomeprazole (as magnesium dihydrate).
GORDEX 40mg is available in the market in concentration 40mg/Tablet and in the form of Capsules (Hard Gelatin).

JULPHAR (GULF PHARMACEUTICAL INDUSTRIES) is the producer of GORDEX 40mg and it is imported from UAE, The most popular alternatives of GORDEX 40mg are listed downward .

Mode Of Action

Esomeprazole is a PPI that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in the gastric parietal cell. It is the S-isomer of omeprazole.

Indication

Heartburn
Acid Related Dyspepsia
Peptic ulcer disease
Zollinger-Ellison syndrome
Gastroesophageal reflux disease (GERD)
Helicobacter pylori infection
Erosive Esophagitis
Gouty arthritis
Duodenal and Gastric Ulcer.

Precaution

Paediatric; pregnancy, lactation. Malignancy and hepatic impairment. Increased risk of developing certain infections such as community-acquired pneumonia. For patients with severe liver impairment, a dose of 20 mg should not be exceeded. Lactation: Unknown whether esomeprazole is distributed into breast milk; discontinue drug or do not nurse

Side Effects

>10% Headache (2-11%) 1-10% Flatulence (10%)
Indigestion (6%)
Nausea (6%)
Abdominal pain (1-6%)
Diarrhea (2-4%)
Xerostomia (3-4%)
Dizziness (2-3%)
Constipation (2-3%)
Somnolence (1-2%)
Pruritus (1%) <1% Blood and lymphatic system disorders: Agranulocytosis
pancytopenia Blurred vision
GI disorders: Pancreatitis
stomatitis
microscopic colitis Hepatobiliary disorders: Hepatic failure
hepatitis with or without jaundice Anaphylactic reaction/shock GI candidiasis Hypomagnesemia Musculoskeletal disorders: Muscular weakness
myalgia
bone fracture Nervous system disorders: Hepatic encephalopathy
taste disturbance Psychiatric disorders: Aggression
agitation
depression
hallucination Interstitial nephritis Gynecomastia Bronchospasm Skin and subcutaneous tissue disorders: Alopecia
erythema multiforme
hyperhidrosis
photosensitivity
Stevens-Johnson syndrome
toxic epidermal necrolysis (sometimes fatal fatal)

Contra indication

Esomeprazole is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted Benzimidazoles.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Increased risk of digoxin-induced cardiotoxic effects. Increased risk of hypomagnesaemia w/ diuretics. May increase INR and prothrombin time w/ warfarin. May increase serum concentration of tacrolimus, saquinavir, methotrexate. May interfere the elimination of drugs metabolised by CYP2C19 (e.g. diazepam). May decrease the bioavailability of ketoconazole, erlotinib and Fe salts. Potentially Fatal: May decrease serum concentration and pharmacological effects of rilpivirine, atazanavir and nelfinavir. May decrease the antiplatelet effects of clopidogrel.