Talk to your doctor or pharmacist before taking Descontran. Concomitant treatment with drugs that have a potentially hepatotoxic action should be avoided. Do not associate with the consumption of alcoholic beverages. Strictly respect the doses and duration of treatment, You should not use this medicine at a higher dose or for longer than 7 days. This is because one of the products that forms in your body when you take thiocolchicoside in high doses can cause damage to some cells (abnormal number of chromosomes). This has been proven in animal studies and laboratory studies. In humans, this type of cell damage is a risk factor for cancer, fetal harm and fertility problems in men. Talk to your doctor if you have any further questions., The doctor will inform you about all measures related to effective contraception and about the potential risk of pregnancy, If you notice any symptoms that could indicate liver damage during treatment with Descontran (e.g. loss of appetite, nausea, vomiting, abdominal discomfort, fatigue, dark urine, jaundice, itching) you should stop taking Descontran and seek medical advice immediately. . You should tell your doctor if you have any of the following symptoms: Seizures.