DESCONTRAN 500mg/2mg Price

Overview

Welcome to Dwaey, specifically on DESCONTRAN 500mg/2mg page.
This medicine contains an important and useful components, as it consists of
Paracetamol and Thiocolchicosideis available in the market in concentration

Name

Benzoic Acid 6% + Salicylic Acid 3%

Precaution

- Use with caution in patients with hypersensitivity to salicylic acid, benzoic acid, or any other ingredients in the formulation. - Avoid contact with broken or irritated skin. The drug may cause stinging or irritation on compromised skin. - Patients with a history of skin conditions such as eczema, dermatitis, or psoriasis should consult a healthcare provider before use, as this combination can exacerbate irritation in some cases. - For external use only; avoid applying near the eyes, mouth, or mucous membranes. - Children under 2 years of age should not use this product without medical supervision. The safety and efficacy of this combination in children younger than 2 have not been well studied. - Pregnant or breastfeeding women should use this medication only if clearly needed, and under the guidance of a healthcare professional. High systemic absorption of salicylic acid, though unlikely in topical applications, may pose risks during pregnancy. - Prolonged use or overuse of this combination product may lead to systemic absorption, increasing the risk of systemic side effects such as salicylate toxicity, especially if applied over large areas of skin. - Caution should be used when applying the medication to areas with extensive sun exposure, as it may increase skin sensitivity to sunlight and lead to sunburn. - Avoid using other topical products containing salicylic acid or other keratolytic agents unless directed by a healthcare provider, as this could increase the risk of skin irritation.

Indication

- Benzoic Acid 6% and Salicylic Acid 3% are typically indicated for the treatment of superficial skin conditions such as acne vulgaris, warts, and other benign skin lesions. - It is commonly used in the treatment of corns, calluses, and plantar warts, where its keratolytic properties help in the removal of thickened skin. - It is effective in managing seborrheic keratosis and other conditions that involve the overproduction of skin cells. - This combination can also be used as a topical agent for the treatment of folliculitis (inflammation of hair follicles). - For patients with acne, the product works as an exfoliant that helps to unclog pores and reduce the formation of pimples. - The combination can also be used for the treatment of other forms of hyperkeratosis (thickened skin) due to its ability to break down the keratin buildup. - Used as an adjunct to other acne treatments when other therapies alone are insufficient.

Contra indication

- Contraindicated in individuals who are known to be hypersensitive to salicylic acid, benzoic acid, or any of the other ingredients in the formulation. - Not recommended for use in patients with open wounds or severely irritated skin, as the acids in this combination can cause further damage or worsen irritation. - Should not be applied to large areas of broken skin, sunburnt skin, or inflamed skin as it may increase irritation and sensitivity. - Contraindicated in children younger than 2 years of age due to the lack of safety and efficacy data in this age group. - Should not be used in patients with a history of systemic salicylate toxicity, as the topical absorption could exacerbate symptoms in sensitive individuals. - Avoid use in patients with severe kidney impairment or liver dysfunction due to the potential for increased systemic absorption of salicylic acid.

Side Effect

- Local skin irritation, redness, or a mild burning sensation at the site of application is common. - Dryness or peeling of the skin may occur as the salicylic acid works to exfoliate the skin. - Prolonged use may lead to excessive skin peeling, which may result in raw, irritated skin. - Allergic reactions, though rare, may include itching, hives, or swelling at the site of application. - Severe reactions can lead to systemic effects such as dizziness, tinnitus, or gastrointestinal discomfort if too much is absorbed systemically, particularly in the case of prolonged use or application over large areas. - Increased sensitivity to sunlight may occur, leading to sunburn more easily. Patients should be advised to limit sun exposure or wear sunscreen while using the product. - Potential risk of chemical burns or severe irritation if used on areas of sensitive skin, such as the face or mucous membranes.

Pregnancy Category ID

3

Mode of Action

- Benzoic acid has antifungal and antiseptic properties that help to prevent infections in the skin and act as a preservative. - Salicylic acid works as a keratolytic agent, which means it helps to break down the keratin in the skin, thereby facilitating the shedding of dead skin cells and promoting the regeneration of new, healthy skin. - The combination of these two ingredients helps to treat various skin conditions by promoting skin exfoliation, unclogging pores, and reducing inflammation. - Benzoic acid also has mild analgesic properties, which can help to reduce discomfort associated with warts, calluses, and acne lesions. - Salicylic acid’s action as a chemical exfoliant helps reduce the formation of acne and may also assist in treating hyperkeratotic conditions by softening thickened skin and removing debris, which prevents clogging of hair follicles. - Together, these ingredients enhance the skin’s ability to shed excess layers and regenerate, making it more effective for conditions like acne, warts, and other benign skin lesions.

Interaction

- Salicylic acid, as a keratolytic agent, may interact with other topical medications that affect the skin, such as corticosteroids. Combining salicylic acid with steroids could increase the risk of skin irritation or thinning. - Concurrent use with other topical exfoliants (e.g., alpha-hydroxy acids, benzoyl peroxide) should be avoided unless prescribed by a healthcare provider, as it could lead to excessive skin dryness, irritation, or peeling. - Systemic interactions are less likely with topical application, but if the product is used over a large surface area or for prolonged periods, systemic absorption of salicylic acid could interact with other medications metabolized by the liver, particularly anticoagulants (e.g., warfarin) and certain antihypertensive drugs. - Since salicylic acid can affect the excretion of certain drugs in the kidneys, caution is advised when used alongside medications that impact renal function. - Always inform a healthcare provider of all medications being taken, including topical and systemic drugs, to avoid possible interactions.

Pregnancy Category Note

Information not available

Adult Dose

- Typically, the recommended dose for adults is to apply a thin layer of the product to the affected area once or twice daily, depending on the severity of the condition being treated. - For acne vulgaris, the combination is usually applied to the entire affected area or as directed by a healthcare provider. - For warts or other skin lesions, apply a thin layer directly to the lesion and cover with a bandage if necessary. - Do not use more than 1-2 times daily to avoid excessive skin irritation. Overuse may cause peeling, redness, or other adverse reactions. - Dosage may vary depending on the severity of the skin condition. Follow specific instructions provided by a healthcare provider or product label.

Child Dose

- The safety and efficacy of this medication have not been established for children younger than 2 years of age. - For children over the age of 2, the recommended dosage is generally a thin layer of the product applied to the affected area once or twice daily, as tolerated. - The product should be applied sparingly to avoid excessive systemic absorption, especially in children with sensitive skin. - Do not exceed the recommended dose and avoid applying it to large areas of the body. - Always consult a pediatrician before using this medication in children, particularly if the child has underlying skin conditions or if the medication is being considered for use on the face or mucous membranes.

Renal Dose

- There is no specific renal dose adjustment required for topical formulations of benzoic acid and salicylic acid, as systemic absorption is minimal when used as directed. - However, in patients with severe renal impairment, the accumulation of salicylic acid in the system could increase the risk of toxicity. Therefore, it is advisable to consult with a healthcare provider before using this medication in such patients, especially for prolonged use or use over large areas of the skin. - Use with caution in patients with known kidney disease and monitor for signs of systemic absorption, such as tinnitus or dizziness.

Administration

Information not available