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VISCOR 20 Price

Active Substance: Simvastatin.

39
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on VISCOR 20 Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Simvastatin.
VISCOR 20 is available in the market in concentration 20mg/Tablet and in the form of Tablets/Film-coated.

NATIONAL PHARMACEUTICAL INDUSTRIES CO. (SAOG) is the producer of VISCOR 20 and it is imported from OMAN, The most popular alternatives of VISCOR 20 are listed downward .

Mode Of Action

Simvastatin, an antilipemic agent is a competitive inhibitor of HMG-CoA reductase, the enzyme that catalyses the early and rate-limiting step in cholesterol biosynthesis reduces total cholesterol, LDL-cholesterol and triglycerides and increases HDL-cholesterol levels.

Indication

  • Hyperlipidaemias
  • stroke prevention

Precaution

History of liver disease. Increased risk of rhabdomyolysis in severe infection, hypotension, major surgical trauma, uncontrolled seizures or severe metabolic, endocrine and electrolyte disorder. Alcoholism; premenarcheal females; children <10 yr. Discontinue treatment if there is marked or persistent increase in serum-aminotransferase concentrations. Monitoring Parameters Monitor creatine kinase (CK) periodically and LFT. Discontinue if there is significant or persistent increase in CK levels, serum aminotransferase levels or evidence of myopathy. Lactation: Contraindicated; potentially unsafe

Side Effects

  • 1-10% CPK elevation (>3x ULN) (5%)
  • Constipation (2%)
  • Upper respiratory infection (9%)
  • Flatulence (1-2%)
  • Transaminases increased (>3x ULN) (1%)
  • Headache (3-7%)
  • Myalgia (5%)
  • Eczema (5%)
  • Vertigo (5%)
  • Abdominal pain (7%) <1% Myalgia
  • Myopathy
  • Arthralgia
  • Arthritis
  • Eosinophilia
  • Chills
  • Angioedema
  • Rhabdomyolysis
  • Abdominal pain Potentially Fatal: Severe rhabdomyolysis with acute renal failure.

Contra indication

Acute liver disease or unexplained persistent elevations of serum transaminases. Patients of Chinese descent should not take simvastatin 80 mg/day w/ lipid-modifying dose of niacin-containing products (?1 g). Simvastatin 80 mg should not be started in new patients and to those taking lower doses. Concurrent use w/ potent CYP3A4 inhibitors e.g. itraconazole, ketoconazole, posaconazole, clarithromycin, erythromycin, telithromycin, nefazodone, HIV protease inhibitors (e.g. nelfinavir), boceprivir, telaprevir., gemfibrozil, ciclosporin, danazol, grapefruit juice. Pregnancy and lactation.

Pregnancy and lactation

Pregnancy category: X

Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Interaction

May increase bleeding risk w/ anticoagulants. Reduced serum levels w/ bosentan, efavirenz and rifampicin. Increased risk of myopathy and rhabdomyolysis w/ colchicine, amiodarone, verapamil and diltiazem. Increased risk of myopathy w/ amlodipine, fusidic acid. Potential reduction of cytotoxic effect of rituximab. Increased hepatotoxicity w/ ezetimibe. Potentially Fatal: Concurrent use w/ itraconazole, ketoconazole, posaconazole, clarithromycin, erythromycin, telithromycin, nefazodone, niacin, HIV protease inhibitors (e.g. nelfinavir), boceprivir, telaprevir, gemfibrozil, ciclosporin and danazol may increase the risk of myopathy, rhabdomyolysis and acute renal failure.

Alternatives Price List

  • ZOCOR 40mgUAD 167
  • ZOCOR 20mgUAD 92
  • ZOCOR 10mgUAD 84
  • VISCOR 20UAD 39
  • VASTA 20UAD 39

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