Active Substance: Formoterol fumarate dihydrate.
Overview
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This medicine contains an important and useful components, as it consists of
Formoterol fumarate dihydrateis available in the market in concentration
Formoterol Fumarate
Thyrotoxicosis; severe CV disorders e.g. ischaemic heart disease, tachyarrhythmias or severe heart burn; prolonged QT-interval. DM; pregnancy; lactation; children <5 yr; do not initiate or increase the dose during an exacerbation. May produce paradoxical bronchospasm. Lactation: not known if excreted in breast milk, use caution
Asthma,Chronic bronchitis, Emphysema, COPD
Hypersensitivity.
>10% Viral infection (17.2%) 1-10% Bronchitis (4.6%),Chest infection (2.7%),Dyspnea (2.1%),Chest pain (1.9%),Tremor (1.9%),Dizziness (1.6%) Frequency Not Defined Angina,Arrhythmias,Hypo/hypertension,Tachycardia,Hypokalemia,Hyperglycemia,Metabolic acidosis,Headache,Insomnia,Paradoxical bronchospasm,Severe asthma exacerbation
3
Formoterol relaxes the bronchial smooth muscle by selectively acting on beta2-receptors with minimal effect on heart rate. It has a long-acting effect.
Concomitant treatment with xanthine derivatives, steroids or diuretics may potentiate a possible hypokalaemic effect of beta-agonists. Increased susceptibility to cardiac arrhythmias in patients treated with digitalis. Concomitant use with quinidine, disopyramide, procainamide, phenothiazines, antihistamines, MAOI or TCAs can prolong the QT-interval and increase the risk of ventricular arrhythmias. L-dopa, L-thyroxine, oxytocin and alcohol can impair cardiac tolerance towards beta2-sympathomimetics. beta-adrenergic blockers can inhibit the effect of formoterol. Increased risk of arrhythmias in patients receiving concomitant anaesthesia with halogenated hydrocarbons.
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