OXIS 9mcg/Dose TURBUHALER Inhaler/Dry Powder

What is OXIS 9mcg/Dose TURBUHALER

OXIS 9mcg/Dose TURBUHALER is a dry powder inhalation medication containing Formoterol fumarate dihydrate, a long-acting beta-2 adrenergic agonist (LABA). It is designed for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) to improve breathing by relaxing the muscles in the airways.

• Generic Name: Formoterol fumarate dihydrate
• Form: Dry powder inhaler (Turbuhaler)
• Strength: 9 micrograms per dose
• Pack Size: 60 doses per inhaler
• Purpose: Maintenance bronchodilator therapy for asthma and COPD

OXIS 9mcg/Dose TURBUHALER provides rapid onset and prolonged bronchodilation lasting up to 12 hours, making it ideal for twice-daily administration. It is not intended for acute symptom relief but rather for regular use to prevent bronchospasm and maintain open airways.

How to use OXIS 9mcg/Dose TURBUHALER

Proper inhaler technique is critical for effective delivery of medication to the lungs.

• Remove the protective cap from the inhaler.
• Hold the inhaler upright and twist the colored grip fully in one direction, then back until a click is heard. This loads a dose.
• Exhale fully, away from the inhaler, to empty your lungs.
• Place the mouthpiece between your lips and inhale deeply and forcefully to ensure the powder reaches the lungs.
• Remove the inhaler from your mouth and hold your breath for about 10 seconds to allow the medicine to settle in the lungs.
• Exhale slowly and replace the cap securely after use.
• Rinse your mouth with water and spit it out to reduce the risk of oral thrush or irritation.

Use the inhaler regularly as prescribed by your healthcare provider, usually twice daily. Do not use it to treat sudden breathing difficulties. Always carry a short-acting inhaler for emergencies.

Mode of Action OXIS 9mcg/Dose TURBUHALER

Formoterol fumarate dihydrate, the active component, selectively stimulates beta-2 adrenergic receptors in the smooth muscle lining the airways:

• Bronchodilation: Activation of beta-2 receptors causes relaxation of bronchial smooth muscles, leading to airway dilation and easier airflow.
• Rapid onset: Provides symptom relief within 1–3 minutes after inhalation.
• Long duration: The bronchodilatory effect persists for about 12 hours, enabling twice-daily dosing.
• Improved lung function: Helps reduce airway resistance and improves ventilation.

This action makes OXIS effective in managing chronic respiratory diseases by preventing bronchospasm episodes and improving quality of life.

OXIS 9mcg/Dose TURBUHALER Interactions OXIS 9mcg/Dose TURBUHALER

Several drugs can interact with OXIS, potentially altering its effect or increasing risks:

• Beta-blockers: May block Formoterol’s effects and worsen breathing problems.
• Diuretics: Especially non-potassium-sparing types, may increase the risk of hypokalemia when combined with Formoterol.
• Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants: Can enhance cardiovascular side effects like increased heart rate or blood pressure.
• Other sympathomimetic drugs: Concurrent use may increase risk of side effects such as tachycardia or tremors.
• Inhaled corticosteroids: Often used together; ensure appropriate dosing to minimize systemic effects.

Always inform your doctor of all medications you take to prevent potential harmful interactions.

Dosage of OXIS 9mcg/Dose TURBUHALER

Dosage varies depending on the condition and patient response:

• Asthma (Adults and adolescents 12 years and older): 1 inhalation (9 mcg) twice daily.
• COPD (Adults): 1 inhalation twice daily.
• Maximum recommended dose: 2 inhalations per day (18 mcg total).
• Not recommended for: Acute asthma attacks or sudden breathing difficulties.

Dosage adjustments may be needed based on clinical response and tolerability. Consult your healthcare professional for personalized instructions.

Possible side effects of OXIS 9mcg/Dose TURBUHALER

Common side effects include:

• Tremors or shaking
• Headache
• Palpitations or increased heart rate
• Nervousness or anxiety
• Throat irritation or dry mouth

Less common side effects:

• Muscle cramps
• Insomnia
• Dizziness
• Nausea

Rare but serious side effects:

• Paradoxical bronchospasm (worsening breathing)
• Chest pain or arrhythmias
• Allergic reactions such as rash, swelling, or anaphylaxis

If you experience severe or persistent symptoms, seek immediate medical attention.

OXIS 9mcg/Dose TURBUHALER Contraindications OXIS 9mcg/Dose TURBUHALER

• Hypersensitivity to Formoterol or any inhaler component.
• Use as monotherapy in asthma without an inhaled corticosteroid, due to risk of asthma-related death.
• Severe cardiovascular disorders such as unstable angina, arrhythmias, or recent myocardial infarction.
• Thyrotoxicosis or uncontrolled hyperthyroidism.
• History of paradoxical bronchospasm triggered by beta-2 agonists.

Caution is advised in patients with diabetes, epilepsy, or those taking medications affecting potassium levels.

Storage of OXIS 9mcg/Dose TURBUHALER

• Store below 30°C (86°F), away from excessive heat or moisture.
• Keep the inhaler dry; avoid exposure to water or humidity.
• Always replace the protective cap tightly after use to protect the powder.
• Do not freeze or refrigerate the inhaler.
• Keep out of reach of children and pets.
• Dispose of the inhaler responsibly when the dose counter reaches zero or after the expiration date.

Proper storage ensures the medication’s effectiveness and safety throughout its usage period.