LESCOL XL 80mg Price
Active Substance: Fluvastatin (as sodium).
Overview
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This medicine contains an important and useful components, as it consists of
Fluvastatin (as sodium)is available in the market in concentration
Name
Fluvastatin
Precaution
History of liver disease; high alcohol intake. Manage hypothyroidism adequately before starting treatment. Report unexplained muscle pain. Monitor LFTs. Discontinue in case of marked or persistent increase in serum aminotransferase or creatine phosphokinase. Severe renal impairment. Lactation: enters breast milk; contraindicated
Indication
Hyperlipidaemias, Hypercholesterolemia
Contra indication
Acute liver disease; unexplained persistently raised serum aminotransferase concentrations; porphyria; pregnancy; lactation.
Side Effect
1-10% Headache (9%),Dyspepsia (8%),Abdominal pain (5%),Diarrhea (5%),Myalgia (5%),Fatigue (3%),Insomnia (3%),Nausea (3%),Sinusitis (3%),Bronchitis (2%),UTI (2%),Transaminases increased (1.1%) <1% Rash,Back pain,Arthralgia,Myopathy,Rhabdomyolysis,Rupture of tendon,CPK increased,Pharyngitis,Rhinitis,Cough,Constipation,Pancreatitis,Dizziness
Pregnancy Category ID
5
Mode of Action
Fluvastatin acts by competitively inhibiting HMG-CoA reductase, the enzyme for cholesterol synthesis. It reduces total cholesterol, triglycerides, LDL and VLDL concentrations in plasma. It also increases HDL concentrations.
Interaction
Bleeding and increased prothrombin time w/ coumarin anticoagulants. May increase the risk of myopathy and rhabdomyolysis w/ HIV protease inhibitors, colchicine, bezafibrate, ciprofibrate or niacin (nicotinic acid), ciclosporin and fluconazole. Reduced bioavailability w/ concomitant rifampicin.
Pregnancy Category Note
Information not available
Adult Dose
Child Dose
Renal Dose
Administration
