Active Substance: Prednisolone.
Overview
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This medicine contains an important and useful components, as it consists of
Prednisoloneis available in the market in concentration
Prednisolone
Patients with hypothyroidism, cirrhosis, ulcerative colitis, CHF, convulsive disorders, thrombophlebitis, peptic ulcer, elderly. DM, hypertension, psychological disturbances, osteoporosis; pregnancy, lactation. Adrenal suppression and infection. May cause irreversible growth retardation, glaucoma, corneal perforation. Lactation: Excreted in breast milk; use caution
Rheumatoid arthritis, Multiple sclerosis, Allergic and inflammatory disorders, Nephrotic syndrome, Idiopathic thrombocytopenic purpura, Joint inflammations, Moderate to severe asthma, Infantile spasms
Live vaccines; herpes simplex keratitis, systemic infections.
Acne,Adrenal suppression,Delayed wound healing,Diabetes mellitus,GI perforation,Glucose intolerance,Hepatomegaly,Hypokalemic alkalosis,Increased transaminases,Insomnia,Menstrual irregularity,Myopathy,Neuritis,Osteoporosis,Peptic ulcer,Perianal pruritus,Pituitary adrenal axis suppression,Pseudotumor cerebri (on withdrawal),Psychosis,Seizure,Ulcerative esophagitis,Urticaria,Vertigo,Weight gain Potentially Fatal: Acute adrenal insufficiency precipitated by infection, trauma or surgery in patients on long-term therapy or following cessation of such therapy. CV collapse following rapid IV injection.
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Prednisolone decreases inflammation by inhibition of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It suppresses the immune system by reducing the activity and production of the lymphocytes and eosinophils.
Efficacy may be reduced by phenytoin, phenobarb, rifampicin. Corticoids may reduce the effects of diuretics, hypoglycaemics, anticholinesterases, salicylates.
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