FAMLOGEN 250 Price in UAE

Overview

Welcome to Dwaey, specifically on FAMLOGEN 250 page.
This medicine contains an important and useful components, as it consists of
Famcicloviris available in the market in concentration

Name

Famciclovir INN

Precaution

Renal impairment. Pregnancy. Lactation: Unknown whether drug is excreted in breast milk; caution advised

Indication

Genital herpes, Herpes zoster, Herpes labialis, CMV infections, Mucocutaneous herpes

Contra indication

Hypersensitivity. Lactation.

Side Effect

>10% Headache (23%),Nausea (13%) 1-10% Diarrhea (2-9%),Abdominal pain (8%),Dysmenorrhea (<8%),Vomiting (1-5%),Flatulence (5%),Pruritus (4%),Rash (3%),Paresthesia (3%),Neutropenia (3%),Increased transaminases (2-3%),Increased bilirubin (2%),Fatigue (1%) <1% Arthralgia,Confusion,Dizziness,Erythema multiforme,Hallucinations,Jaundice,Rigors,Thrombocytopenia,Upper respiratory tract infection

Pregnancy Category ID

Mode of Action

Famciclovir rapidly undergoes biotransformation to penciclovir, which has inhibitory activity against HSV types 1 (HSV-1) and 2 (HSV-2) varicella-zoster virus (VZV). Thymidine kinase then phosphorylates penciclovir to a monophosphate form, which is then converted to penciclovir triphosphate. This inhibits HSV-2 DNA polymerase by competing with deoxyguanosine triphosphate, thus inhibiting herpes viral DNA synthesis and replication.

Interaction

Reduced renal excretion resulting to increased plasma concentration w/ probenecid. Raloxifen may reduce the formation of penciclovir, the active metabolite of famciclovir.