CRESTOCAN 20 mg price in UAE

Overview

Welcome to Dwaey, specifically on CRESTOCAN 20 mg Tablet/Film coated page.
This medicine contains an important and useful components, as it consists of Rosuvastatin .
CRESTOCAN 20 mg is available in the market in concentration 20 mg/tablet and in the form of Tablet/Film coated.

ADCAN PHARMA is the producer of CRESTOCAN 20 mg and it is imported from UAE, The most popular alternatives of CRESTOCAN 20 mg are listed downward .

Mode Of Action

Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis. It increases the number of hepatic LDL receptors on the cell surface, enhancing uptake and catabolism of LDL. It also decreases apolipoprotein B, triglycerides and increases HDL.

Indication

Hyperlipidaemias
Primary hypercholesterolaemia (heterozygous familial hypercholesterolaemia)
mixed dyslipidaemia
homozygous familial hypercholesterolaemia
Stroke prevention

Precaution

Patients w/ predisposing factors for myopathy (e.g. untreated hypothyroidism, renal impairment), history of chronic liver disease and alcoholism. Monitoring Parameters Monitor creatine kinase (CK) periodically and LFT. Discontinue treatment if there is significant or persistent increase in CK levels, serum aminotransferase levels or evidence of myopathy. Lactation Contraindicated

Side Effects

>10% Myalgia (3-13%) 1-10% Arthralgia (10%)
Diabetes mellitus
new onset (3%)
Pharyngitis (9%)
Headache (6%)
Asthenia (up to 5%)
Dizziness (4%)
CPK increased (3%)
Nausea (3%)
Abdominal pain (2%)
ALT increased (2%)
Constipation (2%)
Flulike illness (2%)
UTI (2%) <1% Jaundice
Myopathy
Rhabdomyolysis Potentially Fatal: Rhabdomyolysis with acute renal failure.

Contra indication

Severe renal impairment, active liver disease, unexplained persistent elevations of serum transaminases; hypersensitivity. Pregnancy, lactation.

Pregnancy and lactation

Pregnancy category: X

Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Interaction

May increase serum levels of warfarin and oral contraceptives. May increase serum levels w/ itraconazole, HIV protease inhibitors. May decrease serum levels w/ erythromycin and antacids. May increase risk of myopathy w/ fenofibrate, niacin. Potentially Fatal: Increased risk of rhabdomyolysis w/ gemfibrozil and ciclosporin.