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TORVACOL 20 Price

Active Substance: Atorvastatin (as calcium).

104
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on TORVACOL 20 Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Atorvastatin (as calcium).
TORVACOL 20 is available in the market in concentration 20mg/Tablet and in the form of Tablets/Film-coated.

THE JORDANIAN PHARMACEUTICAL MANUFACTURING COMPANY is the producer of TORVACOL 20 and it is imported from JORDAN, The most popular alternatives of TORVACOL 20 are listed downward .

Mode Of Action

Atorvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyses the conversion of HMG-CoA to mevalonate. This results in the induction of the LDL receptors and stimulation of LDL catabolism, leading to lowered LDL-cholesterol levels.

Indication

  • Primary hypercholesterolemia (heterozygous familial and nonfamilial)
  • Mixed Dyslipidemia
  • Homozygous familial hypercholesterolemia
  • Hypertriglyceridemia
  • Familial hypercholesterolemia
  • Cardiovascular event prevention
  • Primary dysbetalipoproteinemia

Precaution

Patients who consume substantial quantities of alcohol. History of liver disease. Patients with risk factors for myopathy or rhabdomyolysis. Hypothyroidism should be properly managed prior to starting statin therapy. Children <10 yr. Premenarcheal females. Lactation: Because of the potential for adverse reactions in nursing infants, women taking this drug should not breastfeed; contraindicated in nursing mothers.

Side Effects

  • >10% Diarrhea (5-14%)
  • Nasopharyngitis (4-13%)
  • Arthralgia (4-12%) 1-10% Insomnia (1-5%)
  • Urinary tract infection (4-8%)
  • Nausea (4-7%)
  • Dyspepsia (3-6%)
  • Increased transaminases (2-3%)
  • Muscle spasms (2-5%)
  • Musculoskeletal pain (2-5%)
  • Myalgia (3-8%)
  • Limb pain (3-8%)
  • Pharyngolaryngeal pain (1-4%) Frequency Not Defined Angina
  • Syncope
  • Dyspnea
  • Myopathy
  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Myositis Potentially Fatal: Thrombocytopenia. Rhabdomyolysis with acute renal failure.

Contra indication

Hypersensitivity, active liver disease or unexplained persistent elevations of serum transaminase, porphyria, pregnancy, lactation.

Pregnancy and lactation

Pregnancy category: X

Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Interaction

May increase risk of myopathy and rhabdomyolysis w/ CYP3A4 potent inhibitor (e.g. HIV or HCV protease inhibitors, itraconazole, clarithromycin), fenofibrate, colchicines, fixed combination of lopinavir/ritonavir. May decrease plasma concentration w/ CYP3A4 inducer (e.g. rifampicin, efavirenz). May significantly increase AUC and peak plasma concentration of digoxin. Increased AUC for norethindrone and ethinyl estradiol. Potentially Fatal: Increased risk of myopathy or rhabdomyolysis w/ ciclosporin, gemfibrozil, telaprevir, tipranavir.

Alternatives Price List

  • VASTOR 40 UAD 122
  • VASTOR 20 UAD 104
  • VASTOR 10 UAD 65
  • TULIP 40mgUAD 122
  • TULIP 20mgUAD 104

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