ALDACTONE 100 price in UAE

Overview

Welcome to Dwaey, specifically on ALDACTONE 100 Tablets page.
This medicine contains an important and useful components, as it consists of Spironolactone.
ALDACTONE 100 is available in the market in concentration 100mg/Tablet and in the form of Tablets.

SEARLE PHARMACEUTICALS is the producer of ALDACTONE 100 and it is imported from UK, The most popular alternatives of ALDACTONE 100 are listed downward .

Mode Of Action

Spironolactone acts on the distal renal tubules as a competitive antagonist of aldosterone. It increases the excretion of sodium chloride and water while conserving potassium and hydrogen ions.

Indication

Oedema
Hirsutism
Hypertension
Hepatic cirrhosis w/ ascites and oedema
Hyperaldosteronism
Severe CHF
Hypokalaemia

Precaution

Patient at risk of developing hyperkalaemia and acidosis, w/ DM. Renal and hepatic impairment. Elderly. Pregnancy and lactation. Patient Counselling This drug may cause dizziness and somnolence, if affected do not drive or operate machinery. Monitoring Parameters Monitor serum electrolytes periodically; BP, renal function. Lactation: Metabolite excreted into breast milk; discontinue breastfeeding or do not use drug

Side Effects

Drowsiness
dizziness
headache
lethargy
leg cramps
GI disturbances (e.g. diarrhoea
cramps)
ataxia
mental confusion
rashes
pruritus
alopecia
hyponatraemia
electrolyte disturbances
gynaecomastia
hirsutism
menstrual irregularities
breast pain
deepening of the voice
impotence
leucopenia (including agranulocytosis)
thrombocytopenia
transient elevation in BUN concentration. Rarely
breast enlargement. Potentially Fatal: Hyperkalaemia.

Contra indication

Anuria, hyperkalaemia, acute or progressive renal insufficiency. Addison's disease.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Increased risk of hyperkalaemia w/ other K-sparing diuretics or K supplements, ACE inhibitors, angiotensin II receptor antagonists, trilostane, heparin, LMWH. Increased risk of nephrotoxicity w/ ciclosporin, NSAIDs. Increased risk of lithium toxicity. May reduce ulcer-healing properties of carbenoxolone. May increase serum level of digoxin. May reduce vascular response to norepinephrine. Concurrent use w/ colestyramine may cause hyperkalaemic metabolic acidosis. Potentiation of orthostatic hypotension may occur w/ barbiturates or narcotics. Potentially Fatal: May enhance hyperkalaemic effect w/ eplerenone. Increased risk of lithium toxicity when used concurrently.