NITROCINE 1mg/ml Price

Overview

Welcome to Dwaey, specifically on NITROCINE 1mg/ml Infusion/Solution for page.
This medicine contains an important and useful components, as it consists of Glyceryl trinitrate.
NITROCINE 1mg/ml is available in the market in concentration 1mg/ml and in the form of Infusion/Solution for.

SCHWARZ PHARMA GmbH is the producer of NITROCINE 1mg/ml and it is imported from GERMANY, The most popular alternatives of NITROCINE 1mg/ml are listed downward .

Mode Of Action

Glyceryl trinitrate acts on the enzyme nitric oxide stimulating guanylate cyclase in the vascular smooth muscle cells resulting in the relaxation of smooth muscles. It reduces venous return (preload) and facilitates subendocardial blood flow with redistribution into ischaemic areas. It relieves coronary vasospasm and dilates arterioles reducing afterload. It is useful for relief and prevention of anginal attacks.

Indication

• Angina pectoris
• Acute myocardial infarction
• Severe hypertension
• Pulmonary edema.

Precaution

Severe hepatic or renal impairment, hypothyroidism, malnutrition, hypothermia. Cerebrovascular disease, lung disease or cor pulmonale. Pregnancy, lactation, glaucoma, mitral valve prolapse, cardiac tamponade, syncope. Gradual withdrawal in patients who have received prolonged high dose infusions. Avoid prolonged excessive hypotension. Nitrate-free interval is recommended in patients on continuous treatment with nitrates to reduce risk of tolerance. Lactation: not known whether the drug crosses into breast milk, use caution

Side Effects

• Common Headache
• Hypotension
• Tachycardia
• Dizziness
• Lightheadedness
• Blurred vision
• Flushing
• N/V
• Nervousness
• Xerostomia Serious Methemoglobinemia (rare)
• Syncope
• Prolonged bleeding time
• Exfoliative dermatitis
• Unstable angina
• Rebound hypertension
• Thrombocytopenia Sublingual Tabs/Spray: Dry mouth
• localised burning sensation. Buccal tablets: Delayed dissolution
• may be swallowed by mistake. Potentially Fatal: Hypotension
• paradoxical bradycardia
• impaired respiration
• syncope and collapse.

Contra indication

Hypersensitivity. Severe hypotension, heart failure, marked anaemia, hypertrophic obstructive cardiomyopathy, cerebral haemorrhage or head trauma, low cardiac output secondary to hypovolaemia, inferior MI with right ventricular involvement, raised intracranial pressure. Concomitant use with phosphodiesterase type-5 inhibitors.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks