Active Substance: Adenosine.
Overview
Welcome to Dwaey, specifically on ADENIV 6mg/2ml page.
This medicine contains an important and useful components, as it consists of
Adenosineis available in the market in concentration
Adenosine
Pregnancy; heart transplant patients; patients on dipyridamole (lower initial dose of adenosine 0.5-1 mg); atrial fibrillation or flutter with accessory pathway (conduction along anomalous pathway may increase). Lactation: Potential for serious adverse reactions in nursing infants; decision to interrupt nursing after administration of adenosine or not should take into account importance of drug to mother.
Paroxysmal supraventricular tachycardia, Supraventricular tachycardia
2nd or 3rd degree AV block and sick sinus syndrome (unless pacemaker fitted), asthma, hypersensitivity.
>10% Flushing (18%),Dyspnea (12%) 1-10% Chest pain (7%),HA (2%),Lightheadedness (2%),Dizziness (1%),Tingling in arms (1%),Numbness (1%),Nausea (3%) <1% Hypotension,Palpitations,Apprehension,Head pressure,Chest pain,Hyperventilation,Blurred vision,Burning sensation,Heaviness in arms, neck & back pain,Metallic taste,Tightness in throat,Pressure in groin,Sweating
3
Adenosine acts rapidly to slow down conduction through the AV node via the A1 receptors. It also mediates peripheral and coronary vasodilatation by stimulating the A2 receptors. Extremely short plasma half-life (<10 sec) permits dosage titration during IV use every 1-2 min and causes no concern of cumulative effect through repeated dosing.
Adenosine effects antagonised by methylxanthines like caffeine, theophylline, etc. Concomitant carbamazepine may increase the risk of heart block. Potentially Fatal: Adenosine effects are potentiated by dipyridamole.
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