Active Substance: Gabapentin.
Overview
Welcome to Dwaey, specifically on GABATA 400 page.
This medicine contains an important and useful components, as it consists of
Gabapentinis available in the market in concentration
Gabapentin
Discontinuation or transfer from other antiepileptics, history of psychotic illness; renal impairment; pregnancy. Gradual withdrawal over at least 7 days to prevent an increase in seizure frequency. Lactation: Enters breast milk; use with caution
Epilepsy, Neuropathic pain, Partial Seizures, Hot flashes, Fibromyalgia, Postherpetic Neuralgia, Pain from diabetic neuropathy.
Hypersensitivity. Lactation.
>10% Ataxia (1-13%),Dizziness (16-20%),Drowsiness (5-21%),Fatigue (11-15%),Somnolence (16-20%) 1-10% Diplopia (6-10%),Nystagmus (6-10%),Tremor (6-10%),Amblyopia (1-5%),Back pain (1-5%),Constipation (1-5%),Depression (1-5%),Dry mouth (1-5%),Dysarthria (1-5%),Dyspepsia (1-5%),Hostility (5-8% children),Hyperkinesia (3-5%),Increased appetite (1-5%),Leukopenia (1-5%),Myalgia (1-5%),Nervousness (1-5%),Peripheral edema (1-5%),Pharyngitis (1-5%),Pruritus (1-5%),Rhinitis (1-5%),Vasodilation (1-5%),Weight gain (1-5%),Abnormal vision (>1%),Anorexia (>1%),Arthralgia (>1%),Asthenia (>1%),HTN (>1%),Malaise (>1%),Paresthesia (>1%),Purpura (>1%),Vertigo (>1%)
3
Gabapentin is structurally related to the neurotransmitter GABA but is neither a GABA agonist nor antagonist. High affinity gabapentin binding sites are located throughout the brain. These sites correspond to the presence of voltage-gated Ca channels particularly controlling the ?-2/?-1 subunit. This channel appears to be located presynaptically and may modulate the release of excitatory neurotransmitters which participate in epileptogenesis and nociception.
May increase plasma level w/ morphine. Reduced absorption w/ antacids.
Information not available