0.9% SODIUM CHLORIDE INJECTION USP Price

Overview

Welcome to Dwaey, specifically on 0.9% SODIUM CHLORIDE INJECTION USP Infusion/Solution for page.
This medicine contains an important and useful components, as it consists of Sodium chloride.
0.9% SODIUM CHLORIDE INJECTION USP is available in the market in concentration 9mg/ml and in the form of Infusion/Solution for.

WELLPHARMA MEDICAL SOLUTIONS LLC is the producer of 0.9% SODIUM CHLORIDE INJECTION USP and it is imported from UAE, The most popular alternatives of 0.9% SODIUM CHLORIDE INJECTION USP are listed downward .

Mode Of Action

Captopril competitively inhibits the conversion of angiotensin I (ATI) to angiotensin II (ATII), thus resulting in reduced ATII levels and aldosterone secretion. It also increases plasma renin activity and bradykinin levels. Reduction of ATII leads to decreased Na and water retention. This promotes vasodilation and BP reduction.

Indication

• Hypertension
• Congestive heart failure
• Post Myocardial infarction
• Diabetic nephropathy

Precaution

Patients on diuretics or with sodium depletion should discontinue diuretics or increase sodium intake prior to initiation of therapy. Renal impairment, SLE and other autoimmune collagen disorders and during concurrent use of immunosuppressant or leucopenic drugs, monitor WBC count and urinary protein before and during therapy. Lactation. Porphyria. Severe CHF. Discontinue as soon as pregnancy detected; during the second and third trimesters of pregnancy, drugs that act directly on the renin-angiotensin have been associated with fetal injury that includes hypotension, neonatal skull hypoplasia, anuria, reversible or irreversible renal failure, and death Lactation: enters breast milk/not recommended (AAP states compatible with nursing)

Side Effects

• >10% Hyperkalemia (1-11%) 1-10% Hypersensitivity rxns (4-7%)
• Skin rash (4-7%)
• Dysgeusia (2-4%)
• Hypotension (1-2.5%)
• Pruritus (2%)
• Cough (0.5-2%)
• Chest pain (1%)
• Palpitations (1%)
• Proteinuria (1%)
• Tachycardia (1%) Frequency Not Defined Cardiac arrest
• Orthostatic hypotension
• Ataxia
• Confusion
• Depression
• Somnolence
• Angioedema
• Photosensitivity
• Neutropenia
• ARF if renal artery stenosis
• Renal impairment
• Impotence Potentially Fatal: Neutropenia
• usually occurs within 3 mth of starting therapy especially in patients with renal dysfunction or collagen diseases. Hyperkalaemia. Anaphylactic reactions.

Contra indication

Known hypersensitivity to the drug. Bilateral renal artery stenosis, hereditary angioedema; renal impairment; pregnancy.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Pregnancy Category: C; D in 2nd & 3rd trimesters