Active Substance: Ivermectin .
Overview
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This medicine contains an important and useful components, as it consists of
Ivermectin
is available in the market in concentration
Ivermectin
Concurrent Loa loa infection, impaired blood-brain barrier function due to infection. Lactation: Enters breast milk (AAP Committee states compatible with nursing)
Ascariasis, Strongyloidiasis, Filariasis, Scabies, Onchocerciasis, Gnathostomiasis
Hypersensitivity. Pregnancy and lactation. Childn <15 kg body weight.
Diarrhoea, nausea, vomiting, dizziness, pruritus, urticaria, rash, arthralgia, fever, myalgia, asthenia, postural hypotension, tachycardia, oedema, lymphadenopathy, sore throat, cough, headache, somnolence, transient eosinophilia, raised liver enzyme values.
3
Ivermectin selectively binds and with high affinity to glutamate-gated chloride ion channels, which occur in invertebrate nerve and muscle cells leading to an increase in the permeability of cell membranes to chloride ions with hyperpolarization of the nerve or muscle cell and, ultimately, death of the parasite.
Bioavailability may be increased by alcohol, levamisole.
Information not available