Overview

Welcome to Dwaey, specifically on DESFERAL 500mg Injection page.
This medicine contains an important and useful components, as it consists of Desferrioxamine Mesilate.
DESFERAL 500mg is available in the market in concentration 500mg/Vial and in the form of Injection.

CIBA GEIGY is the producer of DESFERAL 500mg and it is imported from SWITZERLAND, The most popular alternatives of DESFERAL 500mg are listed downward .

Mode Of Action & Indication

Deferoxamine has a high affinity for ferric iron and forms chelates or stable water-soluble complexes with iron and other trivalent metal ions eg, aluminum. It removes free and bound iron from haemosiderin and ferritin, increasing the excretion of iron in urine and bile.

Indication

• Iron overload
• Aluminum overload
• Iron poisoning

Precaution

Impaired renal function; may color the urine reddish-brown, exacerbate aluminum-related encephalopathy and precipitate seizure (prophylactic with antiepileptic if at risk); susceptible to infection; monitor urinary excretion of iron, ophthalmological, audiological and cardiac function examinations; pregnancy.

Side Effects

• Rapid IV injection: Flushing
• urticaria
• hypotension and shock. SC or IM injection: Local pain. Prolonged SC: Pruritus
• erythema and swelling. GI disorders
• dysuria
• fever
• allergic skin rashes
• tachycardia
• cardiac arrhythmias
• convulsions and leg cramps; visual disturbances
• cataract formation
• hearing loss; may retard growth in very young childn. Pulmonary syndrome with high IV doses.

Contra indication

Severe renal disease or anuria.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks