Overview

Welcome to Dwaey, specifically on DERM-AID 0.5% Cream page.
This medicine contains an important and useful components, as it consists of Hydrocortisone.
DERM-AID 0.5% is available in the market in concentration 5mg/g and in the form of Cream.

EGO PHARMACEUTICALS PTY. LTD. is the producer of DERM-AID 0.5% and it is imported from AUSTRALIA, The most popular alternatives of DERM-AID 0.5% are listed downward .

Mode Of Action & Indication

Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.

Indication

• Corticosteroid-responsive dermatoses
• hypersensitivity reactions such as angioedema
• status asthmaticus
• Soft tissue inflammation
• Joint inflammations
• Primary or secondary adrenocortical insufficiency
• Acute adrenocortical insufficiency
• Shock unresponsive to conventional therapy
• Congenital adrenal hyperplasia
• Hypercalcemia associated with cancer
• Nonsuppurative thyroiditis
• Rheumatic Disorders
• Dermatologic Diseases (Allergic States
• Severe seborrheic dermatitis
• Severe psoriasis
• Pemphigus
• Severe erythema multiforme)
• Control of severe or incapacitating allergic conditions (Bronchial asthma
• Contact dermatitis
• Atopic dermatitis
• Serum sickness
• Seasonal or perennial allergic rhinitis
• Drug hypersensitivity reactions
• Urticarial transfusion reactions
• Acute noninfectious laryngeal edema)
• Ophthalmic Diseases (Herpes zoster ophthalmicus
• Iritis
• iridocyclitis
• Chorioretinitis
• Diffuse posterior uveitis and choroiditis
• Optic neuritis)
• Gastrointestinal Diseases
• Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy
• Loeffler's syndrome
• Aspiration pneumonitis
• Hematologic Disorders (Acquired
• autoimmune hemolytic anemia
• Idiopathic thrombocytopenic purpura in adults
• Secondary thrombocytopenia
• Erythroblastopenia)
• Neoplastic Diseases (Leukemias and lymphomas in adults
• Acute leukemia of childhood)
• Edematous States
• Acute exacerbations of multiple sclerosis

Precaution

CHF, hypertension, DM, epilepsy, elderly, patients on prolonged therapy. Gradual withdrawal, pregnancy and lactation. Lactation: Drug enters breast milk; use with caution

Side Effects

• Sodium and fluid retention. Potassium and calcium depletion. Muscle wasting
• weakness
• osteoporosis. GI disturbances and bleeding. Increased appetite and delayed wound healing. Bruising
• striae
• hirsutism
• acne
• flushing. Raised intracranial pressure
• headache
• depression
• psychosis
• menstrual irregularities. Hyperglycaemia
• glycosuria
• DM
• obesity
• moon-face
• buffalo hump. Suppression of pituitary-adrenocortical system. Growth retardation in childn (prolonged therapy). Increased susceptibility for infection. Topical use: Dermal atrophy
• local irritation
• folliculitis
• hypertrichosis. Inhaled corticosteroids: May cause hoarseness
• candidiasis of mouth and throat. Topical application to the eye: Can produce corneal ulcers
• raised IOP and reduced visual function. Intralesional injection: Local hypopigmentation of deeply pigmented skin. Intra-articular injection: Joint damage
• fibrosis esp in load bearing joints. Potentially Fatal: Abrupt withdrawal leading to acute adrenal insufficiency. Rapid IV Inj may cause CV collapse.

Contra indication

Viral/fungal infections, tubercular or syphilitic lesions, bacterial infections unless used in conjunction with appropriate chemotherapy.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks