ASACOL 1600 mg Price

Overview

Welcome to Dwaey, specifically on ASACOL 1600 mg Tablets/Modified Release page.
This medicine contains an important and useful components, as it consists of Mesalazine.
ASACOL 1600 mg is available in the market in concentration 1600 mg /Tablet and in the form of Tablets/Modified Release.

TILLOTTS PHARMA GMBH is the producer of ASACOL 1600 mg and it is imported from GERMANY, The most popular alternatives of ASACOL 1600 mg are listed downward .

Mode Of Action

Mesalazine is considered to be the active moiety of sulfasalazine. The mechanism of action is uncertain, but may be due to its ability to inhibit local chemical mediators of the inflammatory response especially leukotriene synthesis in the GI mucosa. Action may be topical in terminal ileum and colon rather than systemic.

Indication

• Ulcerative colitis
• Hairy cell leukaemia

Precaution

Mild to moderate impaired renal or hepatic function (test serum creatinine before treatment, every 3 mth for 1st yr, every 6 mth for next 4 yr, then annually). Elderly; active peptic ulcer; pregnancy, lactation; patients predisposed to pericarditis or myocariditis. Counsel patients to report any unexplained bleeding, bruising, purpura, sore throat, fever or malaise during treatment; perform blood count and stop treatment if blood dyscrasias suspected. Counsel patients taking delayed release tablets to report repeatedly unbroken or partially broken tablets in their faeces. Pyloric stenosis may delay release into colon.

Side Effects

• Abdominal pain (if new abdominal pain - consider pancreatitis); headache
• nausea; flu; fatigue; fever
• rash; sore throat; diarrhoea; joint pain; dizziness; bloating; back pain; haemorrhoids; itching; rectal pain
• constipation; hair loss; intolerance syndrome; peripheral oedema; UTI; myocarditis
• pre-existing pericarditis; pancreatitis; nephritis; hepatitis; lupus-like syndrome; alopecia; myalgia
• arthralgia; increased liver enzyme values. Potentially Fatal: Blood dyscrasias
• aplastic anaemia
• agranulocytosis; renal toxicity.

Contra indication

Hypersensitivity to mesalazine, salicylates and sulfasalazine. Severe impaired renal (CrCl < 20 ml/min) or hepatic function. Children <2 yr.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.