Overview

Welcome to Dwaey, specifically on ZOCIN 250mg Capsules (Hard Gelatin) page.
This medicine contains an important and useful components, as it consists of Azithromycin.
ZOCIN 250mg is available in the market in concentration 250mg/Capsule and in the form of Capsules (Hard Gelatin).

ADVANCED PHARMACEUTICAL INDUSTRIES CO. LTD. is the producer of ZOCIN 250mg and it is imported from JORDAN, The most popular alternatives of ZOCIN 250mg are listed downward .

Mode Of Action & Indication

Azithromycin is a semisynthetic azalide antibiotic. It blocks transpeptidation by binding to 50s ribosomal subunit of susceptible organisms and disrupting RNA-dependent protein synthesis at the chain elongation step.

Indication

• Bacterial infections
• bacterial endocarditis
• typhoid fever
• community-acquired pneumonia
• uncomplicated gonorrhea
• streptococcal pharyngitis/tonsillitis
• COPD
• acute bacterial sinusitis
• acute otitis media
• uncomplicated UTI
• Uncomplicated gonorrhea
• PID
• non-gonococcal urethritis
• chancroid
• acute salmonellosis
• cervicitis
• babesiosis
• chlamydial infections
• pelvic inflammatory disease
• PID
• traveler's diarrhea

Precaution

May increase the risk of Torsades de pointes and fatal heart arrhythmias in patients w/ prolonged QT interval, low K or Mg blood levels, slow heart rate and medication treating abnormal heart rhythms. Impaired hepatic and renal function. Pregnancy and lactation. Monitoring Parameters Liver function tests, CBC w/ differential. Lactation: Unknown whether drug is excreted into breast milk; use with caution

Side Effects

• >10% High single dose therapy Diarrhea (52.8%)
• Nausea (32.6%)
• Abdominal pain (27%)
• Loose stool (19.1%) 1-10% Cramping (2-10%)
• Vaginitis (2-10%)
• Dyspepsia (9% with single high dose therapy)
• Flatulence (9% with single high dose therapy)
• Vomiting (6.7% with single high dose therapy)
• Malaise (1.1%) <1% Agitation
• Allergic reaction
• Anemia
• Anorexia
• Candidiasis
• Chest pain
• Conjunctivitis
• Constipation
• Dermatitis (fungal)
• Dizziness
• Eczema
• Edema
• Enteritis
• Facial edema
• Fatigue
• Gastritis
• Headache
• Hyperkinesia
• Hypotension
• Increased cough
• Insomnia
• Leukopenia
• Malaise
• Melena
• Mucositis
• Nervousness
• Oral candidiasis
• Pain
• Palpitations
• Pharyngitis
• Pleural effusion
• Pruritus
• Pseudomembranous colitis
• Rash
• Rhinitis
• Seizures
• Somnolence
• Urticaria
• Vertigo Potentially Fatal: Angioedema and cholestatic jaundice.

Contra indication

Known hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic. Coadministration w/ pimozide. History of cholestatic jaundice/hepatic dysfunction associated w/ prior use of azithromycin.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.