Overview

Welcome to Dwaey, specifically on UNI-Z 500 mg Tablet page.
This medicine contains an important and useful components, as it consists of Azithromycin.
UNI-Z 500 mg is available in the market in concentration 500 mg/Tablet and in the form of Tablet.

CSPC OUYI PHARMACEUTICAL CO., LTD. is the producer of UNI-Z 500 mg and it is imported from CHINA, The most popular alternatives of UNI-Z 500 mg are listed downward .

Mode Of Action & Indication

Azithromycin is a semisynthetic azalide antibiotic. It blocks transpeptidation by binding to 50s ribosomal subunit of susceptible organisms and disrupting RNA-dependent protein synthesis at the chain elongation step.

Indication

• Bacterial infections
• bacterial endocarditis
• typhoid fever
• community-acquired pneumonia
• uncomplicated gonorrhea
• streptococcal pharyngitis/tonsillitis
• COPD
• acute bacterial sinusitis
• acute otitis media
• uncomplicated UTI
• Uncomplicated gonorrhea
• PID
• non-gonococcal urethritis
• chancroid
• acute salmonellosis
• cervicitis
• babesiosis
• chlamydial infections
• pelvic inflammatory disease
• PID
• traveler's diarrhea

Precaution

May increase the risk of Torsades de pointes and fatal heart arrhythmias in patients w/ prolonged QT interval, low K or Mg blood levels, slow heart rate and medication treating abnormal heart rhythms. Impaired hepatic and renal function. Pregnancy and lactation. Monitoring Parameters Liver function tests, CBC w/ differential. Lactation: Unknown whether drug is excreted into breast milk; use with caution

Side Effects

• >10% High single dose therapy Diarrhea (52.8%)
• Nausea (32.6%)
• Abdominal pain (27%)
• Loose stool (19.1%) 1-10% Cramping (2-10%)
• Vaginitis (2-10%)
• Dyspepsia (9% with single high dose therapy)
• Flatulence (9% with single high dose therapy)
• Vomiting (6.7% with single high dose therapy)
• Malaise (1.1%) <1% Agitation
• Allergic reaction
• Anemia
• Anorexia
• Candidiasis
• Chest pain
• Conjunctivitis
• Constipation
• Dermatitis (fungal)
• Dizziness
• Eczema
• Edema
• Enteritis
• Facial edema
• Fatigue
• Gastritis
• Headache
• Hyperkinesia
• Hypotension
• Increased cough
• Insomnia
• Leukopenia
• Malaise
• Melena
• Mucositis
• Nervousness
• Oral candidiasis
• Pain
• Palpitations
• Pharyngitis
• Pleural effusion
• Pruritus
• Pseudomembranous colitis
• Rash
• Rhinitis
• Seizures
• Somnolence
• Urticaria
• Vertigo Potentially Fatal: Angioedema and cholestatic jaundice.

Contra indication

Known hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic. Coadministration w/ pimozide. History of cholestatic jaundice/hepatic dysfunction associated w/ prior use of azithromycin.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.