SYMBICORT TURBUHLER 160/4.5mcg/dose Price

Overview

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This medicine contains an important and useful components, as it consists of Budesonide, Formoterol fumarate dihydrate.
SYMBICORT TURBUHLER 160/4.5mcg/dose is available in the market in concentration 160mcg, 4.5mcg/dose and in the form of Inhaler/Dry Powder.

ASTRAZENECA AB is the producer of SYMBICORT TURBUHLER 160/4.5mcg/dose and it is imported from SWEDEN, The most popular alternatives of SYMBICORT TURBUHLER 160/4.5mcg/dose are listed downward .

Mode Of Action

Budesonide is a corticosteroid that has mainly glucocorticoid activity. It prevents and controls inflammation by controlling the rate of protein syntheis, decreasing the migration of polymorphonuclear leucocytes/fibroblasts and reversing capillary permeability. Formoterol fumarate is a selective beta2-adrenergic agonist. It causes bronchodilation by catalysing the conversion of adenosine triphosphate to cyclic-3', 5'-adenosine monophosphate (cyclic AMP) resulting in bronchial smooth muscle relaxation.

Indication

• Asthma
• COPD

Precaution

Treatment with Budesonide and Formoterol combination should not be initiated to treat a severe exacerbation or if patients have significantly worsening or acutely deteriorating asthma. May produce paradoxical bronchospasm which is life-threatening. Caution when used in patients with CV diseases, especially coronary insufficiency, cardiac arrhythmias and hypertension. Chronic use may further decrease bone mineral content when used in patients with advanced age, osteoporosis, poor nutrition, sedentary lifestyle or tobacco use. May reduce growth velocity when used in paediatric patients. Caution when used in patients with active or quiescent tuberculosis infection of the respiratory tract, untreated systemic fungal, bacterial, viral or parasitic infections, or ocular herpes simplex. Pregnancy and lactation. Lactation: No data; weigh risks of therapy against benefits, and either discontinue drug or do not nurse

Side Effects

• >10% Upper respiratory tract infection (URTI) (8-11%)
• Headache (7-11%)
• Nasopharyngitis (7-11%) 1-10% Pharyngolaryngeal pain (6-9%)
• Stomach discomfort (1-7%)
• Sinusitis (5-6%)
• Oral candidiasis (1-6%)
• Bronchitis (5%)
• Viral URTI (4%)
• Backache (2-3%)
• Influenza (2-3%)
• Nasal congestion (2-3%)
• Vomiting (1- 3%)

Contra indication

Primary treatment of status asthmaticus or other acute episodes of asthma. Hypersensitivity to Budesonide, Formoterol or to Lactose.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks