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SUPRAZOLE 200mg Price

Active Substance: Metronidazole.

13
UAD , based on 7541 reviews.
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Overview

Welcome to Dwaey, specifically on SUPRAZOLE 200mg Tablets page.
This medicine contains an important and useful components, as it consists of Metronidazole.
SUPRAZOLE 200mg is available in the market in concentration 200mg/Tablet and in the form of Tablets.

KUWAIT SAUDI PHARMACEUTICAL INDUSTRIES CO. (KSPICO) is the producer of SUPRAZOLE 200mg and it is imported from KUWAIT, The most popular alternatives of SUPRAZOLE 200mg are listed downward .

Mode Of Action

Metronidazole is converted to reduction products that interact w/ DNA to cause destruction of helical DNA structure and strand leading to a protein synthesis inhibition and cell death in susceptible organisms. It is active against most anaerobic protozoa, some gm+ve, gm-ve and facultative anaerobes.

Indication

  • Pneumonia
  • Giardiasis
  • Peptic ulcer disease
  • Peritonitis
  • H. pylori infection
  • Rosacea
  • Septicemia
  • Endometritis
  • Aspiration pneumonia
  • Lung abscess
  • Empyema
  • Bone and Joint Infections
  • Surgical Prophylaxis
  • Amoebiasis
  • Bacterial vaginosis
  • Balantidiasis
  • Blastocystis hominis infection
  • Trichomoniasis
  • Acute dental infections
  • Acute necrotising ulcerative gingivitis
  • Anaerobic bacterial infections
  • Antibiotic-associated colitis
  • Fungating tumours
  • Leg ulcers and pressure sores
  • Diverticulitis
  • Diabetic foot ulcer
  • Meningitis and brain abscesses
  • endocarditis

Precaution

Patients with CNS diseases; discontinue IV therapy if abnormal neurologic symptoms occur. History of seizure disorder. Evidence or a history of blood dyscrasias; perform total and differential leukocyte counts before and after treatment. Severe hepatic impairment; monitor plasma levels. Predisposition to oedema (inj contains sodium). Prolonged use may result in fungal or bacterial superinfection. Excreted in human milk; not recommended

Side Effects

  • GI disturbances e.g. nausea
  • unpleasant metallic taste
  • vomiting
  • diarrhoea or constipation. Furred tongue
  • glossitis
  • and stomatitis due to overgrowth of Candida. Rarely
  • antibiotic-associated colitis. Weakness
  • dizziness
  • ataxia
  • headache
  • drowsiness
  • insomnia
  • changes in mood or mental state. Numbness or tingling in the extremities
  • epileptiform seizures (high doses or prolonged treatment). Transient leucopenia and thrombocytopenia. Hypersensitivity reactions. Urethral discomfort and darkening of urine. Raised liver enzyme values
  • cholestatic hepatitis
  • jaundice. Thrombophlebitis (IV). Potentially Fatal: Anaphylaxis.

Contra indication

History of hypersensitivity to metronidazole or other nitroimidazole derivatives. Pregnancy (1st trimester) and lactation.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Interaction

Concurrent use w/ disulfiram may produce psychotic reactions. May potentiate the effect of oral anticoagulants. May increase risk of lithium toxicity. May reduce the renal clearance resulting to increased toxicity of 5-fluorouracil. May increase serum levels of ciclosporin. May increase plasma levels of busulfan resulting to severe busulfan toxicity. Enhanced metabolism w/ phenobarbital and phenytoin resulting to decreased serum concentrations.

Alternatives Price List

  • SUPRAZOLE 200mgUAD 13
  • SUPRAZOLE 200mg UAD 17
  • SUPPLIN 500mgUAD 14
  • SUPPLIN 500mgUAD 16
  • SUPPLIN 250mgUAD 12

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