(Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag) Intravenous Infusion

What is (Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag)

(Baxter) Glucose 5% w/v Intravenous Infusion is a sterile, non-pyrogenic solution containing glucose monohydrate, formulated for intravenous administration via a Viaflo bag. This product is typically used in clinical settings to restore fluid balance, provide caloric energy, or serve as a diluent for compatible intravenous medications.

• Active Ingredient: Glucose (Dextrose Monohydrate) 5% w/v
• Form: Intravenous Infusion
• Packaging: 20 Viaflo Bags x 500 ml
• Indications:
  • Treatment of dehydration when fluid replacement is necessary
  • Source of calories in patients unable to consume food orally
  • Carrier solution for IV drug administration

The solution is isotonic, providing a moderate source of carbohydrates without causing hemolysis or tissue damage when administered correctly. It is especially valuable in postoperative care, pediatric hydration, or in patients with restricted oral intake.

How to use (Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag)

Administration of (Baxter) Glucose 5% w/v should be performed under medical supervision, using aseptic technique to prevent contamination. The infusion rate and total volume should be tailored based on the patient’s clinical status, age, weight, and fluid balance.

• Route: Intravenous (IV) infusion via a peripheral or central vein
• Preparation:
  • Ensure the Viaflo bag is intact and solution is clear
  • Do not use if the solution is discolored or contains particles
  • Use sterile equipment for connection
• Administration Tips:
  • Adjust the flow rate according to patient’s tolerance
  • Monitor for signs of fluid overload or electrolyte imbalances
  • Infusion should be discontinued if any adverse reaction occurs

Always consult healthcare protocols and consider concurrent medical conditions, such as diabetes mellitus, when determining the volume and duration of glucose administration.

Mode of Action (Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag)

Glucose, a monosaccharide, serves as a key energy source for cellular metabolism. Upon administration, the solution enters the bloodstream, where glucose is rapidly distributed to tissues and organs for utilization in various physiological processes.

• Primary Action: Provides immediate caloric energy (approximately 170 kcal/L)
• Metabolic Pathway:
  • Absorbed by cells via insulin-regulated glucose transporters
  • Metabolized through glycolysis into pyruvate and ATP
  • Excess glucose stored as glycogen or converted to fat
• Fluid Balance: Due to its isotonicity, it distributes evenly in extracellular fluid compartments, aiding in rehydration without significant osmotic shifts
• Clinical Relevance: Especially useful in hypoglycemia, starvation, or postoperative recovery for maintaining energy balance

As a non-electrolyte solution, it doesn't disrupt the body's ionic equilibrium and can be combined with electrolyte additives when required. Glucose's quick metabolization helps restore vital functions, especially in acute care scenarios.

(Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag) Interactions (Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag)

While generally safe, (Baxter) Glucose 5% w/v Intravenous Infusion may interact with medications, disease states, or metabolic pathways. It is crucial to evaluate the compatibility of any drug or additive before co-administration.

• Drug Interactions:
  • Insulin: Enhances cellular glucose uptake, potentially leading to hypoglycemia
  • Diuretics: May alter fluid and glucose balance, requiring careful monitoring
  • Corticosteroids: Can induce hyperglycemia, reducing glucose infusion tolerance
• Incompatibilities:
  • Do not mix with blood products
  • Avoid combining with drugs that are not pH compatible or that precipitate in glucose solutions
• Conditions of Concern:
  • Diabetes mellitus
  • Renal impairment
  • Congestive heart failure (risk of fluid overload)

Pharmacodynamic interactions should also be considered in polypharmacy settings. Always consult compatibility charts before co-administering intravenous medications.

Dosage of (Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag)

Dosage of (Baxter) Glucose 5% w/v varies based on the patient's clinical condition, age, weight, hydration status, and metabolic needs. It should only be determined by a healthcare professional.

• Adults:
  • Typically 500–1000 ml over 24 hours for hydration or energy support
  • May increase based on caloric requirement, up to 2–3 liters/day
• Pediatrics:
  • 10–100 ml/kg/day depending on age and condition
  • Flow rate should not exceed renal excretory capacity
• Elderly:
  • Initiate at lower volumes due to risk of fluid overload

Infusion rate is usually set at 1.5–3 ml/kg/hour unless specific needs dictate otherwise. Electrolyte supplementation may be added based on laboratory findings. Continuous monitoring of blood glucose and fluid status is essential during therapy.

Possible side effects of (Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag)

Although generally well tolerated, (Baxter) Glucose 5% w/v may cause side effects, especially when administered inappropriately or in patients with comorbidities.

• Common Side Effects:
  • Localized injection site reactions (e.g., redness, pain, swelling)
  • Mild fluid retention or puffiness
  • Temporary rise in blood glucose levels
• Serious Adverse Effects:
  • Hyperglycemia: Particularly in diabetics or patients with impaired glucose metabolism
  • Fluid overload: May result in pulmonary edema or heart failure
  • Electrolyte disturbances: Especially hyponatremia or hypokalemia if not monitored
• Rare but Severe:
  • Anaphylactic reactions (extremely rare)
  • Phlebitis or thrombosis at the injection site

Prompt medical attention should be sought if any severe reaction occurs. Regular monitoring and careful dosing minimize the risk of side effects.

(Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag) Contraindications (Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag)

The use of (Baxter) Glucose 5% w/v Intravenous Infusion is contraindicated in certain medical conditions where glucose administration may exacerbate underlying issues.

• Absolute Contraindications:
  • Hyperglycemia not responsive to insulin
  • Known hypersensitivity to glucose or any component of the solution
  • Severe dehydration with significant electrolyte depletion
• Relative Contraindications:
  • Uncontrolled diabetes mellitus
  • Intracranial or intraspinal hemorrhage (risk of hyperosmolar effects)
  • Acute stroke or head trauma where glucose regulation is critical

In these scenarios, alternative fluids or lower glucose concentrations may be required. Always review patient history and metabolic status before initiating therapy.

Storage of (Baxter) Glucose 5% w/v Intravenous Infusion (Viaflo bag)

Proper storage is essential to maintain the sterility, efficacy, and stability of (Baxter) Glucose 5% w/v Intravenous Infusion.

• Storage Conditions:
  • Store below 25°C (77°F)
  • Do not freeze
  • Protect from light if possible
• Packaging Integrity:
  • Use only if the Viaflo bag is intact and solution is clear
  • Discard any unused portion after opening
  • Do not reconnect partially used bags
• Shelf Life:
  • Refer to product label for expiration date
  • Do not use beyond the printed expiry

Proper inventory management and adherence to hospital protocols help ensure safe usage of intravenous fluids like (Baxter) Glucose 5% w/v.