ANANASE 22mg Price

Overview

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This medicine contains an important and useful components, as it consists of
Bromelainsis available in the market in concentration

Name

Benzoyl Peroxide 4%

Precaution

Before using **Benzoyl Peroxide 4%**, it is important to consult a healthcare provider, especially if the patient has any underlying skin conditions or is using other topical medications. The following precautions should be noted: - **Skin Irritation**: Benzoyl Peroxide can cause **skin dryness**, **redness**, **peeling**, or **stinging**, especially during the first few weeks of use. If irritation persists or worsens, it is essential to consult with a healthcare provider. - **Sun Sensitivity**: Benzoyl Peroxide can increase **sensitivity to the sun**, raising the risk of **sunburn**. Patients should use sunscreen or protective clothing when outdoors and avoid prolonged sun exposure. - **Avoid Eye Contact**: Benzoyl Peroxide should not be applied near the eyes, mouth, or mucous membranes. If contact occurs, rinse immediately with plenty of water. Avoid applying to broken or irritated skin. - **Pregnancy and Lactation**: The use of **Benzoyl Peroxide** during pregnancy should be discussed with a healthcare provider. While topical use is generally considered safe, the potential effects on fetal development or breastfeeding infants have not been conclusively studied. - **Allergic Reactions**: Individuals who are allergic to Benzoyl Peroxide or its ingredients should avoid its use. Signs of a severe allergic reaction include **itching**, **swelling**, **rash**, or **difficulty breathing**, in which case immediate medical attention is needed.

Indication

**Benzoyl Peroxide 4%** is primarily used in the treatment of **acne vulgaris**, a common skin condition characterized by the formation of **pimples**, **blackheads**, **whiteheads**, and **cysts**. Key indications include: - **Acne Treatment**: Benzoyl Peroxide works by reducing **propionibacterium acnes**, the bacteria responsible for acne formation. It helps in decreasing the formation of new acne lesions and speeds up the healing process of existing pimples. - **Comedolytic Agent**: It helps to **unclog pores**, reducing the formation of comedones (blackheads and whiteheads), which are precursors to more severe forms of acne. - **Anti-inflammatory Effect**: Benzoyl Peroxide also has mild **anti-inflammatory** properties, helping to reduce the redness and swelling associated with acne lesions.

Contra indication

Benzoyl Peroxide 4% should not be used in the following cases: - **Hypersensitivity**: It is contraindicated in individuals with a known hypersensitivity to Benzoyl Peroxide or any other ingredients in the formulation. - **Severe Skin Conditions**: It should not be used on broken, inflamed, or severely irritated skin. This includes conditions such as **eczema**, **psoriasis**, or severe sunburn. - **Open Wounds**: Benzoyl Peroxide should not be applied to open wounds, cuts, or mucous membranes as it can cause further irritation and slow down healing. - **Pregnancy (Caution)**: Though generally considered safe for topical use, Benzoyl Peroxide should be used during pregnancy only after consulting a healthcare provider, as its safety in large quantities or over extended periods during pregnancy is not fully established.

Side Effect

Common and severe side effects of **Benzoyl Peroxide 4%** include: - **Common Side Effects**: - **Skin Irritation**: Includes redness, dryness, stinging, peeling, and burning at the site of application. - **Photosensitivity**: Increased sensitivity to sunlight, leading to a higher risk of **sunburn**. - **Itching**: Mild itching can occur as the skin adapts to treatment. - **Dry Skin**: Some users may experience excessive **dryness**, especially in the initial stages of treatment. - **Severe Side Effects**: - **Severe Allergic Reactions**: Rarely, patients may experience a severe allergic reaction, including **swelling** (especially in the face, lips, or throat), **hives**, and difficulty breathing. These require immediate medical attention. - **Severe Skin Peeling**: In rare cases, excessive peeling or **cracking** of the skin can occur, which may lead to further irritation or infection. - **Contact Dermatitis**: Prolonged use or overuse may cause **contact dermatitis**, leading to significant **skin inflammation**, blisters, or crusting.

Pregnancy Category ID

3

Mode of Action

**Benzoyl Peroxide 4%** works through multiple mechanisms to treat acne: - **Antibacterial Action**: Benzoyl Peroxide is effective in reducing the population of **Propionibacterium acnes** (P. acnes), the bacteria that contribute to acne development. The compound releases **oxygen**, which kills the bacteria by creating an unfavorable environment. - **Keratinolytic Effect**: It helps to **break down** the keratin (a protein) that can clog pores and form comedones (blackheads and whiteheads). This facilitates **unclogging pores** and preventing new acne from forming. - **Anti-inflammatory Properties**: Benzoyl Peroxide has mild anti-inflammatory effects, reducing **redness** and **swelling** associated with inflamed acne lesions. - **Comedolytic Action**: By reducing **keratinization** in the skin, it helps prevent the formation of comedones, leading to a reduction in acne breakouts.

Interaction

There are several potential interactions to consider when using **Benzoyl Peroxide 4%**: - **Other Topical Acne Medications**: When used in combination with other acne medications like **retinoids** (e.g., **tretinoin**) or **topical antibiotics** (e.g., **clindamycin**), Benzoyl Peroxide can increase the risk of **skin irritation**. It is advisable to alternate or stagger the application of these products, following healthcare provider guidance. - **Alcohol-Based Products**: Combining Benzoyl Peroxide with **alcohol-based** skin products may increase the likelihood of dryness and irritation. It is advised to avoid using alcohol-based toners or astringents concurrently. - **Hair Dye and Bleaching Agents**: Benzoyl Peroxide can bleach hair, clothing, and bedding. Patients should avoid contact with these items during treatment. - **Sun Sensitizing Drugs**: Medications that increase **photosensitivity**, such as **tetracycline antibiotics** or **diuretics**, may exacerbate the sunburn risk associated with Benzoyl Peroxide.

Pregnancy Category Note

Information not available

Adult Dose

The typical dosing regimen for **Benzoyl Peroxide 4%** varies depending on the patient and the severity of acne: - **Initial Application**: Apply a thin layer to the affected area once or twice daily, starting with **once daily** to minimize irritation. Gradually increase the frequency if the skin tolerates the treatment. - **Application Method**: Cleanse and dry the skin before applying Benzoyl Peroxide. Avoid applying it to areas with broken or irritated skin. - **Maintenance**: After the skin adapts to the treatment, patients can increase usage to **twice daily** if required. - **Duration of Treatment**: Benzoyl Peroxide can be used long-term, but if irritation persists, treatment frequency may need to be reduced.

Child Dose

For pediatric patients, **Benzoyl Peroxide 4%** is used with the following guidelines: - **Age 12 and Older**: Typically, a thin layer is applied once or twice daily, depending on the severity of the acne. Starting with **once daily** is recommended to assess skin tolerance. - **Age Under 12**: The safety and effectiveness of Benzoyl Peroxide in children under 12 years old should be determined by a healthcare provider before use. Lower concentrations may be recommended for younger children, or other treatments may be considered. As always, the pediatric use of Benzoyl Peroxide should be guided by a healthcare professional to ensure appropriate treatment and minimize side effects.

Renal Dose

**Benzoyl Peroxide 4%** is used topically, and systemic absorption is minimal. There are no specific dosage adjustments required for individuals with **renal impairment**. However, it is important to monitor for **local irritation** or excessive drying of the skin in patients with compromised renal function.

Administration

Information not available