SKINOREN 20% Price

Overview

Welcome to Dwaey, specifically on SKINOREN 20% page.
This medicine contains an important and useful components, as it consists of
Azelaic acidis available in the market in concentration

Name

Azelaic Acid 20%

Precaution

- **Skin Sensitivity**: Azelaic acid 20% should be used with caution in individuals with sensitive skin or conditions like rosacea, as it may cause irritation, redness, or a stinging sensation when first applied. - **Avoid Eye Contact**: Azelaic acid 20% should be kept away from the eyes, mouth, and mucous membranes. If it comes into contact with these areas, rinse thoroughly with water to prevent irritation. - **Dry Skin**: If you have dry or peeling skin, azelaic acid may worsen these conditions, leading to further dryness and discomfort. It’s important to monitor skin hydration and apply a moisturizer if needed. - **Pregnancy and Breastfeeding**: Azelaic acid is generally considered safe for use during pregnancy and breastfeeding. However, as with any medication, it should be used under the supervision of a healthcare provider. - **Sun Sensitivity**: Azelaic acid may increase sensitivity to sunlight. Patients using azelaic acid 20% should apply sunscreen daily to protect against sunburn and minimize the risk of irritation caused by UV exposure. - **Other Skin Treatments**: Combining azelaic acid with other topical treatments that cause skin irritation, such as retinoids, alpha-hydroxy acids (AHAs), or benzoyl peroxide, may increase the risk of dryness, peeling, or irritation. Always consult with a healthcare provider before combining treatments.

Indication

- **Acne Treatment**: Azelaic acid 20% is widely used to treat mild to moderate acne vulgaris. It helps to reduce the number of pimples and blackheads by clearing blocked pores, reducing inflammation, and inhibiting the growth of acne-causing bacteria (Propionibacterium acnes). - **Rosacea**: Azelaic acid 20% is also used to treat rosacea, a skin condition characterized by redness, pimples, and visible blood vessels. It helps to reduce the inflammation and redness associated with this condition. - **Hyperpigmentation**: Azelaic acid has skin-lightening effects and is used to treat hyperpigmentation conditions such as melasma, post-inflammatory hyperpigmentation, and dark spots caused by acne. It works by inhibiting melanin production and promoting skin tone evenness. - **Keratosis Pilaris**: Azelaic acid is sometimes used to treat keratosis pilaris, a condition that causes rough, bumpy skin, especially on the arms, thighs, and face. It helps by normalizing skin cell turnover and reducing clogged pores.

Contra indication

- **Hypersensitivity**: Azelaic acid 20% should be avoided in individuals who are hypersensitive or allergic to azelaic acid or any other component of the formulation. Allergic reactions may include redness, itching, swelling, or rash. - **Active Eczema or Dermatitis**: If the skin is actively inflamed, broken, or irritated due to eczema or other dermatological conditions, azelaic acid should not be applied, as it may further exacerbate irritation or cause discomfort. - **Eye Conditions**: Azelaic acid should not be used near the eyes or mucous membranes. Patients with eye conditions, such as conjunctivitis or corneal abrasions, should avoid contact with the product to prevent irritation. - **Pregnancy and Breastfeeding**: While azelaic acid is considered safe during pregnancy and breastfeeding, it’s important to consult with a healthcare provider before use to determine whether it is appropriate for individual cases, particularly during the first trimester.

Side Effect

- **Skin Irritation**: Common side effects include mild burning, stinging, or tingling sensations at the application site. These effects typically subside after continued use, but they may be bothersome, especially when starting treatment. - **Dryness and Peeling**: Azelaic acid 20% may cause dryness and peeling of the skin, particularly during the first few weeks of treatment. It’s important to keep the skin well-moisturized to reduce this effect. - **Redness and Swelling**: Some users may experience temporary redness or swelling at the site of application, especially when the skin is sensitive or irritated. - **Itching and Rash**: Occasionally, azelaic acid may cause itching or a rash. If these symptoms persist or worsen, the treatment should be discontinued, and a healthcare provider should be consulted. - **Hypopigmentation**: Rarely, prolonged use of azelaic acid may lead to lightening of the skin in the treated area, resulting in hypopigmentation. This effect is more common in people with darker skin tones and should be monitored. - **Allergic Reactions**: Although rare, azelaic acid can cause more severe allergic reactions, including hives, swelling of the face or lips, and difficulty breathing. If any of these symptoms occur, seek immediate medical attention.

Pregnancy Category ID

2

Mode of Action

- Azelaic acid 20% is a dicarboxylic acid that works through multiple mechanisms to improve skin conditions such as acne, rosacea, and hyperpigmentation. - **Antibacterial Effects**: Azelaic acid inhibits the growth of *Propionibacterium acnes*, a bacteria that contributes to acne formation. By reducing bacterial proliferation, it helps to prevent new acne lesions. - **Anti-inflammatory**: Azelaic acid reduces inflammation in the skin, which is especially beneficial in treating inflammatory skin conditions like rosacea. It helps to calm the redness and swelling that typically accompanies rosacea. - **Keratinization Regulation**: Azelaic acid helps to normalize the shedding of skin cells in the follicles, reducing the likelihood of blocked pores, which is a key factor in acne formation. It can prevent the build-up of keratin, a protein that can cause clogged pores and pimples. - **Melanin Inhibition**: Azelaic acid reduces the production of melanin, the pigment responsible for skin color. This makes it effective in treating hyperpigmentation conditions, including dark spots, melasma, and post-inflammatory hyperpigmentation.

Interaction

- **Other Topical Treatments**: When used with other topical products, such as retinoids, benzoyl peroxide, or AHAs, azelaic acid may increase skin irritation. It is advised to introduce new products gradually or consult a healthcare provider before combining treatments. - **Alcohol**: Alcohol-based skin products can increase dryness and irritation when used in combination with azelaic acid, so it is best to avoid alcohol-based toners or astringents during treatment. - **Topical Corticosteroids**: Combining azelaic acid with topical steroids may enhance the skin’s susceptibility to irritation. However, for some individuals with rosacea, a doctor may recommend using both treatments, but this should only be done under medical supervision. - **Sun Exposure**: Azelaic acid may make the skin more sensitive to the sun, and using it in combination with other sun-sensitive medications or treatments (like certain antibiotics or diuretics) may increase the risk of sunburn. Always use sunscreen during the day while using azelaic acid.

Pregnancy Category Note

Information not available

Adult Dose

- **Topical Application**: Azelaic acid 20% should be applied as a thin layer to the affected area twice daily (morning and night). After cleansing and drying the skin, apply a small amount to the face or other treated areas, avoiding the eyes and mouth. - **Acne**: For the treatment of acne, azelaic acid should be used consistently for at least 4-6 weeks to see noticeable results. However, it may take up to 3 months for full effects to be achieved. - **Rosacea**: For rosacea, azelaic acid 20% can be applied twice a day to the affected areas, and results may take several weeks to become apparent. Improvement in redness and inflammation can occur with continued use. - **Hyperpigmentation**: When used for hyperpigmentation, azelaic acid should be applied to the affected skin areas and may take several weeks to show visible improvements in skin tone.

Child Dose

- **Use in Children**: Azelaic acid 20% is not typically recommended for use in children under the age of 12 unless directed by a healthcare provider. For children above 12, the application is similar to adults – apply a thin layer of the product to the affected areas twice a day. - **Acne Treatment**: In adolescents with acne, azelaic acid 20% can be an effective treatment when combined with other acne management strategies. The typical dose is a small amount applied to the affected areas after cleansing. - **Rosacea and Hyperpigmentation**: For children with rosacea or hyperpigmentation, a healthcare provider should assess the condition and determine the appropriate treatment plan, ensuring that azelaic acid is safe for use based on the child's skin type and condition.

Renal Dose

- Azelaic acid 20% is a topical medication and is not significantly absorbed into the bloodstream, so renal dose adjustments are generally not necessary. However, if there are any concerns about kidney function or if the individual has a history of kidney disease, consultation with a healthcare provider is recommended before use. - Given the minimal systemic absorption, there are no specific renal contraindications or dose adjustments for topical azelaic acid.

Administration

Information not available