SANDOSTATIN LAR 20mg Price in UAE

Overview

Welcome to Dwaey, specifically on SANDOSTATIN LAR 20mg page.
This medicine contains an important and useful components, as it consists of
Octreotide (as acetate)is available in the market in concentration

Name

Octreotide

Precaution

Renal disease; risk of gall bladder disease; DM; hypothyroidism. Pregnancy, lactation, children, elderly. Monitor levels of vitamin B12 during long term therapy. Lactation: Whether octreotide crosses into breast milk is not known; avoid giving to lactating women

Indication

Acromegaly, Variceal haemorrhage, Secretory neoplasms, Following pancreatic surgery, HIV-associated diarrhoea

Contra indication

Hypersensitivity.

Side Effect

>10% Gallbladder problems (>60%): Decreased gallbladder contractility, gallstones, cholecystitis, cholestatic hepatitis,Dysglycemia (25%),Hypothyroidism (25%),Bradycardia (25%) 1-10% ECG changes (10%),Arrhythmia (9%),Pancreatitis,Upper respiratory tract infection,Fatigue,Headache,Malaise,Rash,Diarrhea,Nausea,Vomiting,Pain at injection site,Joint pain,Blurred vision

Pregnancy Category ID

Mode of Action

Octreotide is a synthetic analogue of somatostatin which acts by suppressing basal and stimulated secretion of growth hormone (GH). It also suppresses LH response to gonadotrophin-releasing hormone and reduces the secretion of gastrin, vasoactive intestinal peptide (VIP), insulin, glucagon, secretin, motilin and pancreatic polypeptide.

Interaction

Dosage adjustment of concurrent therapy may be necessary with calcium channel blockers, oral hypoglycaemics, ?-blockers, diuretics. May increase concentration of bromocriptine. Potentially Fatal: Requirements of insulin may be reduced requiring careful blood-glucose monitoring. Reduction in ciclosporin bioavailability and efficacy.