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AMNORA 5 mg Price

Active Substance: Amlodipine besylate .

71
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on AMNORA 5 mg Tablet page.
This medicine contains an important and useful components, as it consists of Amlodipine besylate .
AMNORA 5 mg is available in the market in concentration 5 mg/tablet and in the form of Tablet .

ANNORA PHARMA FZ-LLC is the producer of AMNORA 5 mg and it is imported from UAE, The most popular alternatives of AMNORA 5 mg are listed downward .

Mode Of Action

Amlodipine relaxes peripheral and coronary vascular smooth muscle. It produces coronary vasodilation by inhibiting the entry of Ca ions into the slow channels or select voltage-sensitive channels of the vascular smooth muscle and myocardium during depolarisation. It also increases myocardial oxygen delivery in patients w/ vasospastic angina.

Indication

  • Mild to moderate hypertension
  • Chronic stable and vasospastic angina
  • Raynaud's disease
  • Coronary Artery Disease
  • HTN
  • Stroke prevention

Precaution

Impaired liver or renal function, CHF, sick-sinus syndrome, severe ventricular dysfunction, hypertrophic cardiomyopathy, severe aortic stenosis. Caution when used in patients with idiopathic hypertrophic subaortic stenosis. Elderly, children. Pregnancy, lactation. Use in renal failure: Although Amlodipine is excreted primarily via kidney, mild renal impairment does not appear to have an effect on the plasma concentrations. Severe renal impairment may however require a dosage reduction. Amlodipine is not dialyzable. Use in patients with impaired hepatic function: Amlodipine half-life is prolonged in patient with impaired hepatic function. Amlodipine should therefore be administered at lower (5mg) initial dose in these patients. Use in heart failure: An increased number of pulmonary oedema has been reported. Lactation: Unknown whether drug is excreted in milk; use not recommended

Side Effects

  • >10% Edema (1.8-10.8%)
  • Pulmonary edema (7-15%) 1-10% Headache (7.3%)
  • Fatigue (4.5%)
  • Palpitations (0.7-4.5%)
  • Dizziness (1.1-3.4%)
  • Nausea (2.9%)
  • Flushing (0.7-2.6%)
  • Abdominal pain (1.6%)
  • Somnolence (1.4%)
  • Male sexual disorder (1-2%)
  • Drowsiness (1%)
  • Pruritus (1-2%)
  • Skin rash (1-2%)
  • Muscle cramps (1-2%)
  • Muscle weakness (1-2%) Potentially Fatal: Hypotension
  • bradycardia
  • conductive system delay and CCF.

Contra indication

Hypersensitivity to Amlodipine or other calcium channel antagonist, Severe hypertension.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Plasma concentrations may be elevated w/ CYP3A4 inhibitors (e.g. azole antifungals, ritonavir). Concomitant therapy w/ simvastatin may increase risk of myopathy including rhabdomyolysis. May increase ciclosporin plasma levels and conivaptan.

Alternatives Price List

  • AMNORA 5 mg UAD 36
  • AMNORA 5 mg UAD 71
  • AMNORA 10 mg UAD 59

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