Active Substance: Sulphacetamide sodium.
Overview
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This medicine contains an important and useful components, as it consists of
Sulphacetamide sodiumis available in the market in concentration
Sulphacetamide Sodium 20% Eye prep
Elderly. History of allergy or asthma; G6PD deficiency; renal and hepatic impairment. Prolonged therapy requires CBC and urinalysis with microscopic examination. Maintain adequate fluid intake. Pregnancy, lactation.
Conjunctivitis, Blepharitis, Ocular infections
Hypersensitivity; infants <2 mth.
Burning, stinging, conjunctivitis, corneal ulcers, irritation, conjunctival hyperaemia. Systemic absorption from inflamed conjunctiva. Potentially Fatal: Stevens-Johnson syndrome.
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Sulfacetamide has bacteriostatic effect on a wide range of gram-positive and gram-negative organisms. It interferes with nucleic acid synthesis thus blocking conversion of PABA to the coenzyme dihydrofolic acid.
Action antagonised by PABA and procaine group of local anaesthetics. PABA present in purulent eye exudates can competitively inhibit the action of sulphacetamide.
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