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PROFINAL COLD & SINUS Price

Active Substance: Ibuprofen, Pseudoephedrine HCl.

11
UAD , based on 7541 reviews.
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Overview

Welcome to Dwaey, specifically on PROFINAL COLD & SINUS Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Ibuprofen, Pseudoephedrine HCl.
PROFINAL COLD & SINUS is available in the market in concentration 200mg, 30mg/Tablet and in the form of Tablets/Film-coated.

JULPHAR (GULF PHARMACEUTICAL INDUSTRIES) is the producer of PROFINAL COLD & SINUS and it is imported from UAE, The most popular alternatives of PROFINAL COLD & SINUS are listed downward .

Mode Of Action

Ibuprofen inhibits synthesis of prostaglandins in body tissues by inhibiting cyclooxygenase-1 and 2. It has anti-inflammatory, analgesic and antipyretic properties.

Indication

  • Rheumatoid arthritis
  • Osteoarthritis
  • Pain
  • Fever
  • Pericarditis
  • Dysmenorrhea
  • Patent ductus arteriosus
  • Inflammation
  • Musculoskeletal and joint disorders

Precaution

Asthma; renal or hepatic disorders; bleeding disorders; CV disease. Pregnancy, lactation. Lactation: Drug excreted into breast milk; use not recommended (American Academy of Pediatrics committee states that drug is compatible with nursing)

Side Effects

  • 1-10% Dizziness (3-9%)
  • Epigastric pain (3-9%)
  • Heartburn (3-9%)
  • Constipation (1-3%)
  • Nausea (3-9%)
  • Rash (3-9%)
  • Tinnitus (3-9%)
  • Edema (1-3%)
  • Fluid retention (1-3%)
  • Headache (1-3%)
  • Vomiting (1-3%) <1% Acute renal failure (sometimes with acute tubular necrosis or hyperkalemia
  • polyuria
  • azotemia
  • cystitis
  • hematuria
  • decreased creatinine clearance
  • elevations in blood urea nitrogen (BUN) or creatinine without other manifestations of renal failure) Agranulocytosis
  • Aplastic anemia
  • Erythema multiforme
  • Erythematous macular rashes
  • Exfoliative dermatitis
  • Hemolytic anemia (with or without positive direct antiglobulin test results)
  • Neutropenia
  • Thrombocytopenia (with or without purpura)
  • Toxic epidermal necrolysis (Lyell syndrome) and photosensitivity reactions Potentially Fatal: Severe CV thrombotic events. Severe GI bleeding
  • ulceration and perforation.

Contra indication

Active peptic ulcer; hypersensitivity. Neonates with congenital heart disease, suspected necrotising enterocolitis and active bleeding (parenteral).

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Pregnancy category: C; D in 3rd trimester or near delivery. At >30 weeks' gestation; may cause premature closure of ductus arteriosus

Interaction

Increased risk of GI bleeding w/ warfarin, corticosteroids, SSRIs and aspirin. May reduce the natriuretic effects of diuretics. Reduced antihypertensive effect of ACE inhibitors and angiotensin II receptor antagonists. May increase toxicity of lithium and methotrexate. Increased nephrotoxicity w/ ciclosporin and tacrolimus.

Alternatives Price List

  • SAPOFEN COLD & FLUUAD 9
  • PROFINAL COLD & SINUSUAD 11
  • NUROFEN COLD AND FLUUAD 11
  • NUROFEN COLD AND FLUUAD 19
  • LEMSIP FLU 12 HRUAD 12

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