PREVENAR 20 Price

Overview

Welcome to Dwaey, specifically on PREVENAR 20 page.
This medicine contains an important and useful components, as it consists of
polysaccharide serotypes 1, 3, 4, 5, 6A, 7F, 8, 9V, 10A, 11A, 12F,14, 15B, 18C, 19A, 19F, 22F, 23F, 33F- polysaccharide serotype 6B/ Vialis available in the market in concentration

Name

Typhoid polysaccharide Vaccine

Precaution

Not for treatment of typhoid fever. Vaccination may not provide full proetction thus, travellers should be advised to take all necessary precautions to avoid contact or ingestion of potentially contaminated food or water sources. IM admin: Caution when used in patients with a history of bleeding disorders, patients on anticoagulant treatment or severely immunocompromised patients. Pregnancy: the effect of Typhoid vaccine on fetal development or reproduction capacity has not been evaluated. Typhoid vaccine should only be used during pregnancy when there is a high risk of infection. Lactation: Not known if excreted in breast ; use caution

Indication

Prevention of typhoid, Active immunisation against typhoid fever caused by Salmonella typhi.

Contra indication

The vaccine protects against typhoid fever caused by Salmonella typhi. Protection is not conferred against paratyphoid fever or illness caused by non-invasive Salmonella. Typhoid vaccine should not be administered to subjects with known hypersensitivity to any component of the vaccine or to subjects having shown signs of hypersensitivity after previous Typhoid vaccine administration, or after any other vaccine containing Vi polysaccharide Salmonella typhi antigens. It may be expected that in patients receiving immunosuppressive treatment or patients with immunodeficiency, an adequate response may not be achieved. The administration of Typhoid vaccine should be postponed in subjects suffering from acute severe febrile illness.

Side Effect

>10% Fever (2-32%),Malaise (4-24%),Headache (16-20%),Soreness (16%),Induration (5-15%),General aches (1-13%) 1-10% Abdominal pain (6.4%),Nausea (<8%),Diarrhea (2.9%),Vomiting (1.5%),Skin rash (1%),Pruritus (<8%),Myalgia (3-7%) <1% Cervical pain,Diarrhea,Flu-like syndrome,Arthralgia,Abdominal pain,Loss of consciousness,Perforated jejunum,Weakness

Pregnancy Category ID

3

Mode of Action

Live attenuateTY21a strain lacks enzyme UDP-4-galactose epimerase, which causes lipopolysaccharide to be synthesized under conditions that induce bacterial autolys; the avirulent strain produces enough lipopolysaccharide to evoke a protective immune response. Conveys active immunity via stimulation of production of endogenously produced antibodies

Interaction

Concurrent use with antibiotics or immunoglobulins may reduce the efficacy of typhoid vaccine. Mefloquine may increase the efficacy of typhoid vaccine. May reduce the diagnostic effect of tuberculin tests. Potentially Fatal: Concurrent use with immunosuppressants may increase the adverse effects of live vaccines.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration