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PREVENAR 13 VACCINE Price

Active Substance: Pneumococcal polysaccharide from each of 13 capsular types of Streptococcus pneumoniae (conjugated to carrier proteins, adsorbed (serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F & 23F).

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Overview

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This medicine contains an important and useful components, as it consists of
Pneumococcal polysaccharide from each of 13 capsular types of Streptococcus pneumoniae (conjugated to carrier proteins, adsorbed (serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F & 23F)is available in the market in concentration

Name

Pneumococcal polysaccharide unconjugated Vaccine

Precaution

Severe renal, hepatic, cardiac, vascular &/or pulmonary dysfunction. Patients on immunosuppressants may be unable to attain required antibody titres. Pregnancy & lactation. Efficacy may be reduced in multiple myeloma, Hodgkin's and non-Hogkin's lymphoma, especially during treatment and in chronic alcoholism. Vaccine should be given 2 wk before starting immunosuppressive treatment or at least 3 mth after treatment completion.

Indication

Prevention of pneumococcal disease

Contra indication

A known allergy to one of the components of the vaccine. Fever or acute disease or a relapse of a chronic disease: It is preferable to postpone vaccination. Vaccination is not recommended for subjects who have been vaccinated within the previous 3 years, unless indicated otherwise. A confirmed or suspected episode of pneumococcal infection is not a contraindication and vaccination should be considered according to the underlying risk status.

Side Effect

Local Reactions at the Injection Site: Pain, erythema (redness), induration and oedema (swelling). These reactions are mild and transient. Rare reactions eg, Arthus phenomenon (severe local reactions) are reversible without after-effects; they mainly occur in subjects with high initial levels of pneumococcal antibody. Moderate and transient hyperthermia (fever) sometimes >39°C which generally occurs very shortly after vaccination and resolves within 24 hrs. Other General Reactions: Adenopathy (inflammation of the lymph nodes), rashes, arthralgia (pain in the joints) and allergic reactions [urticaria, Quincke'soedema (type of urticaria with sudden swelling of the face and neck), anaphylactoid reactions (severe allergic reaction)], headache, muscle pain, malaise, and fatigue have exceptionally been reported.

Pregnancy Category ID

3

Mode of Action

S. pneumoniae capsular antigens stimulate active immune response resulting in production of endogenously produced antibodies

Interaction

Reduce immune response to Zostavax. Immunosuppressives.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration

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