Active Substance: Moxonidine.
Overview
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This medicine contains an important and useful components, as it consists of
Moxonidineis available in the market in concentration
Moxonidine
Renal impairment; avoid abrupt withdrawal (if concomitant treatment with ?-blocker has to be stopped, discontinue ?-blocker first, then moxonidine after few days).
Hypertension
Conduction disorders; bradycardia; severe arrhythmias; severe heart failure; severe ischaemic heart disease; history of angioedema; severe liver or renal impairment; Raynaud's syndrome; intermittent claudication; epilepsy; depression; Parkinson's disease; glaucoma. Pregnancy and lactation.
Dry mouth; headache; fatigue; dizziness; nausea; sleep disturbances; asthenia; vasodilatation; skin reactions; constipation; depression; anxiety; anorexia; parotid pain; vivid dreams; impotence and loss of libido; urinary retention or incontinence; slight orthostastic hypotension; fluid retention.
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Moxonidine is a centrally-acting antihypertensive. It acts in the brainstem through stimulation of central imidazoline receptors to reduce sympathetic tone. Moxonidine also has a low affinity for alpha2-adrenoceptors.
Additive effects with other antihypertensives; may increase sedative effects of benzodiazepines. Effects may be antagonised by TCAs.
Information not available