PANADOL EXTRA WITH OPTIZORB price in UAE

Overview

Welcome to Dwaey, specifically on PANADOL EXTRA WITH OPTIZORB Tablets/Optizorb page.
This medicine contains an important and useful components, as it consists of Paracetamol, Caffeine.
PANADOL EXTRA WITH OPTIZORB is available in the market in concentration 500mg, 65mg/Tablet and in the form of Tablets/Optizorb.

GLAXOSMITHKLINE DUNGARVAN LIMITED is the producer of PANADOL EXTRA WITH OPTIZORB and it is imported from IRELAND, The most popular alternatives of PANADOL EXTRA WITH OPTIZORB are listed downward .

Mode Of Action

Paracetamol exhibits analgesic action by peripheral blockage of pain impulse generation. It produces antipyresis by inhibiting the hypothalamic heat-regulating centre. Its weak anti-inflammatory activity is related to inhibition of prostaglandin synthesis in the CNS. Caffeine, a methylxanthine, is a phosphodiesterase inhibitor. It has an antagonistic effect at central adenosine receptors. It is a CNS and resp stimulant. It has bronchodilating and diuretic properties and it facilitates the performance of muscular work.

Indication

Pain
Fever
Headache
Influenza
Migraine
Sore throat
Backache
Toothache
Rheumatic pain
Dysmenorrhea
Colds

Precaution

Use with caution in alcoholism, hepatic or renal disorder. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease. Excessive intake of caffeine (e.g. coffee, tea and some canned drinks) should be avoided while taking this product.

Side Effects

Haematological reactions including thrombocytopenia
leucopenia
pancytopenia
neutropenia
and agranulocytosis have been reported. Pancreatitis
skin rashes
and other allergic reactions occur occasionally. When the recommended paracetamol-caffeine dosing regimen is combined with dietary caffeine intake
the resulting higher dose of caffeine may increase the potential for caffeine-related adverse effects such as insomnia
restlessness
anxiety
irritability
headaches
gastrointestinal disturbances and palpitations.

Contra indication

Paracetamol is contraindicated in patients with severe renal function impairment and hepatic disease (Viral Hepatitis). Known hypersensitivity to paracetamol or caffeine.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

May reduce serum levels w/ anticonvulsants (e.g. phenytoin, barbiturates, carbamazepine). May enhance the anticoagulant effect of warfarin and other coumarins w/ prolonged use. Accelerated absorption w/ metoclopramide and domperidone. May increase serum levels w/ probenecid. May increase serum levels of chloramphenicol. May reduce absorption w/ colestyramine w/in 1 hr of admin. May cause severe hypothermia w/ phenothiazine.