ORPHACOL 250 mg Price

Overview

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This medicine contains an important and useful components, as it consists of
Cholic acidis available in the market in concentration

Name

Dextrose / Sodium / Potassium

Precaution

Electrolyte Imbalance: Monitor patients for signs of electrolyte disturbances, especially in those with renal impairment or on diuretics. Hyperglycemia: Use with caution in diabetic patients due to the dextrose component. Regular monitoring of blood glucose levels is advised. Fluid Overload: Patients with congestive heart failure or renal insufficiency should be monitored for signs of fluid overload. Allergic Reactions: Assess for any history of hypersensitivity to any of the components. Pediatric Use: Safety and efficacy in children under 2 years have not been established.​

Indication

Respiratory Conditions: Relief of chest congestion associated with common cold, bronchitis, and other respiratory tract infections. Electrolyte Replenishment: Correction of mild to moderate dehydration and electrolyte imbalances. Energy Supply: Provision of calories in patients requiring nutritional supplementation

Contra indication

Hypersensitivity: Known allergy to dextrose, sodium, potassium, guaifenesin, or any excipients. Hyperkalemia: Elevated serum potassium levels. Hypernatremia: Elevated serum sodium levels. Anuria: Absence of urine production, indicating severe renal impairment. Uncontrolled Diabetes Mellitus: Due to the dextrose content

Side Effect

Common: Nausea Vomiting Diarrhea Headache Serious: Electrolyte disturbances (e.g., hyperkalemia, hypernatremia) Hyperglycemia Allergic reactions (e.g., rash, itching, swelling) Renal dysfunction

Pregnancy Category ID

Information not available

Mode of Action

Dextrose: Provides a source of calories and fluid for patients requiring nutritional support. Sodium and Potassium: Essential electrolytes that help maintain fluid balance, nerve function, and muscle function. Guaifenesin: Acts as an expectorant by thinning mucus in the airways, making it easier to cough up and clear from the respiratory tract.​

Interaction

Diuretics: May enhance the risk of electrolyte imbalances. ACE Inhibitors: Concomitant use may increase the risk of hyperkalemia. Insulin and Oral Hypoglycemics: Dextrose may affect blood glucose levels, necessitating dosage adjustments. Lithium: Sodium-containing solutions may affect lithium levels.​

Pregnancy Category Note

Pregnancy: Use only if clearly needed and if the potential benefit justifies the potential risk to the fetus. Lactation: Caution is advised when administering to breastfeeding mothers; consult healthcare provider.​

Adult Dose

Dosage: Administer as directed by a healthcare professional, based on the patient's clinical condition and laboratory results. Frequency: Typically administered every 6 to 8 hours, but may vary depending on the indication and patient response.​

Child Dose

Dosage: Dosing in pediatric patients should be determined by a healthcare provider, considering age, weight, and clinical condition. Note: Safety and efficacy in children under 2 years have not been established

Renal Dose

Adjustment: In patients with renal impairment, dosage adjustments may be necessary to prevent accumulation of electrolytes and fluid overload. Monitoring: Regular monitoring of renal function and electrolyte levels is recommended.​

Administration

Route: Oral administration is common; ensure the patient is able to swallow and has no contraindications to oral intake. Instructions: Shake the bottle well before use to ensure uniform distribution of ingredients. Measure the dose accurately using a proper measuring device. Administer with or without food, as advised by the healthcare provider. Maintain adequate hydration unless contraindicated.​