Active Substance: Indacaterol (as maleate).
Overview
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This medicine contains an important and useful components, as it consists of
Indacaterol (as maleate)is available in the market in concentration
Indacaterol
Not intended for treatment of asthma and acute deterioration of COPD. Patient w/ acutely deteriorating COPD, thyrotoxicosis, seizure disorders, DM, hypokalaemia, CV disorders esp coronary insufficiency, cardiac arrhythmias or HTN. Pregnancy and lactation. Lactation: Unknown whether distributed in human breast milk; use caution
Chronic obstructive pulmonary disease
Patients with asthma without use of a long-term asthma control medication Patients with a history of hypersensitivity to indacaterol or to any of the ingredients.
>10% Post-inhalation cough (24% compared with 7% on placebo) 1-10% Cough (6.5%),Nasopharyngitis (5.3%),Headache (5.1%),Nausea (2.4%),Oropharyngeal pain (2.2%) Potentially Fatal: Asthma-related deaths.
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Indacaterol is a long acting ?2-adrenergic agonist. It relaxes the bronchial smooth muscle by selective action on ?2-receptor which acts locally in the lungs and w/ little effect on heart rate.
Potentiated adverse effects w/ other sympathomimetic agents; possible hypokalaemic effect w/ methylxanthine derivatives, steroids or non-K-sparing diuretics. Other long-acting beta2-adrenergic agonists or medicinal products containing long-acting beta2-adrenergic agonists. Inhibition of the key contributors of indacaterol clearance, CYP3A4 and P-gp.
Information not available