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ONBREZ BREEZHALER 150mcg Price

Active Substance: Indacaterol (as maleate).

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Overview

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This medicine contains an important and useful components, as it consists of
Indacaterol (as maleate)is available in the market in concentration

Name

Indacaterol

Precaution

Not intended for treatment of asthma and acute deterioration of COPD. Patient w/ acutely deteriorating COPD, thyrotoxicosis, seizure disorders, DM, hypokalaemia, CV disorders esp coronary insufficiency, cardiac arrhythmias or HTN. Pregnancy and lactation. Lactation: Unknown whether distributed in human breast milk; use caution

Indication

Chronic obstructive pulmonary disease

Contra indication

Patients with asthma without use of a long-term asthma control medication Patients with a history of hypersensitivity to indacaterol or to any of the ingredients.

Side Effect

>10% Post-inhalation cough (24% compared with 7% on placebo) 1-10% Cough (6.5%),Nasopharyngitis (5.3%),Headache (5.1%),Nausea (2.4%),Oropharyngeal pain (2.2%) Potentially Fatal: Asthma-related deaths.

Pregnancy Category ID

3

Mode of Action

Indacaterol is a long acting ?2-adrenergic agonist. It relaxes the bronchial smooth muscle by selective action on ?2-receptor which acts locally in the lungs and w/ little effect on heart rate.

Interaction

Potentiated adverse effects w/ other sympathomimetic agents; possible hypokalaemic effect w/ methylxanthine derivatives, steroids or non-K-sparing diuretics. Other long-acting beta2-adrenergic agonists or medicinal products containing long-acting beta2-adrenergic agonists. Inhibition of the key contributors of indacaterol clearance, CYP3A4 and P-gp.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration

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