Active Substance: Vitamin - B12 (Mecobalamine).
Overview
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This medicine contains an important and useful components, as it consists of
Vitamin - B12 (Mecobalamine)is available in the market in concentration
Mecobalamin
The medicine should not be used for months if there is no response at all after its use for a certain period of time.
Megaloblastic anaemia, Peripheral neuropathies
Hypersensitivity to any component of this product.
Oral: Anorexia, nausea, vomiting and diarrhoea. Parenteral: Rash, headache, hot sensation, diaphoresis and pain/induration at IM inj site. Potentially Fatal: Anaphylactoid reactions (parenteral).
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Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.
Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.
Information not available