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ALFACORT Price

Active Substance: Hydrocortisone.

10
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on ALFACORT Ointment page.
This medicine contains an important and useful components, as it consists of Hydrocortisone.
ALFACORT is available in the market in concentration 10mg/g and in the form of Ointment.

JULPHAR (GULF PHARMACEUTICAL INDUSTRIES) is the producer of ALFACORT and it is imported from UAE, The most popular alternatives of ALFACORT are listed downward .

Mode Of Action

Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.

Indication

  • Corticosteroid-responsive dermatoses
  • hypersensitivity reactions such as angioedema
  • status asthmaticus
  • Soft tissue inflammation
  • Joint inflammations
  • Primary or secondary adrenocortical insufficiency
  • Acute adrenocortical insufficiency
  • Shock unresponsive to conventional therapy
  • Congenital adrenal hyperplasia
  • Hypercalcemia associated with cancer
  • Nonsuppurative thyroiditis
  • Rheumatic Disorders
  • Dermatologic Diseases (Allergic States
  • Severe seborrheic dermatitis
  • Severe psoriasis
  • Pemphigus
  • Severe erythema multiforme)
  • Control of severe or incapacitating allergic conditions (Bronchial asthma
  • Contact dermatitis
  • Atopic dermatitis
  • Serum sickness
  • Seasonal or perennial allergic rhinitis
  • Drug hypersensitivity reactions
  • Urticarial transfusion reactions
  • Acute noninfectious laryngeal edema)
  • Ophthalmic Diseases (Herpes zoster ophthalmicus
  • Iritis
  • iridocyclitis
  • Chorioretinitis
  • Diffuse posterior uveitis and choroiditis
  • Optic neuritis)
  • Gastrointestinal Diseases
  • Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy
  • Loeffler's syndrome
  • Aspiration pneumonitis
  • Hematologic Disorders (Acquired
  • autoimmune hemolytic anemia
  • Idiopathic thrombocytopenic purpura in adults
  • Secondary thrombocytopenia
  • Erythroblastopenia)
  • Neoplastic Diseases (Leukemias and lymphomas in adults
  • Acute leukemia of childhood)
  • Edematous States
  • Acute exacerbations of multiple sclerosis

Precaution

CHF, hypertension, DM, epilepsy, elderly, patients on prolonged therapy. Gradual withdrawal, pregnancy and lactation. Lactation: Drug enters breast milk; use with caution

Side Effects

  • Sodium and fluid retention. Potassium and calcium depletion. Muscle wasting
  • weakness
  • osteoporosis. GI disturbances and bleeding. Increased appetite and delayed wound healing. Bruising
  • striae
  • hirsutism
  • acne
  • flushing. Raised intracranial pressure
  • headache
  • depression
  • psychosis
  • menstrual irregularities. Hyperglycaemia
  • glycosuria
  • DM
  • obesity
  • moon-face
  • buffalo hump. Suppression of pituitary-adrenocortical system. Growth retardation in childn (prolonged therapy). Increased susceptibility for infection. Topical use: Dermal atrophy
  • local irritation
  • folliculitis
  • hypertrichosis. Inhaled corticosteroids: May cause hoarseness
  • candidiasis of mouth and throat. Topical application to the eye: Can produce corneal ulcers
  • raised IOP and reduced visual function. Intralesional injection: Local hypopigmentation of deeply pigmented skin. Intra-articular injection: Joint damage
  • fibrosis esp in load bearing joints. Potentially Fatal: Abrupt withdrawal leading to acute adrenal insufficiency. Rapid IV Inj may cause CV collapse.

Contra indication

Viral/fungal infections, tubercular or syphilitic lesions, bacterial infections unless used in conjunction with appropriate chemotherapy.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Thiazides may enhance hyperglycaemia and hypokalaemia caused by corticosteroids. Increased incidence of peptic ulcer or GI bleeding with concurrent NSAIDs admin. Response to anticoagulants altered. Dose of antidiabetics and antihypertensives needs to be increased. Decreases serum conc of salicylates and antimuscarinic agents. Ethanol may enhance gastric mucosal irritation. Reduced efficacy with concurrent use of carbamazepine, phenytoin, primidone, barbiturates and rifampicin. Mutual inhibition of metabolism between ciclosporin and corticosteroids increase plasma conc of both drugs. Enhanced effect in women taking oestrogens or oral contraceptives.

Alternatives Price List

  • Oriocort 10mgUAD 78
  • HYDROCORT-20 UAD 28
  • EGOCORT 1%UAD 9
  • DERM-AID 0.5%UAD 6
  • CORTIDERM 1%UAD 5

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