ALFACORT price in UAE

Overview

Welcome to Dwaey, specifically on ALFACORT Ointment page.
This medicine contains an important and useful components, as it consists of Hydrocortisone.
ALFACORT is available in the market in concentration 10mg/g and in the form of Ointment.

JULPHAR (GULF PHARMACEUTICAL INDUSTRIES) is the producer of ALFACORT and it is imported from UAE, The most popular alternatives of ALFACORT are listed downward .

Mode Of Action

Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency.

Indication

Corticosteroid-responsive dermatoses
hypersensitivity reactions such as angioedema
status asthmaticus
Soft tissue inflammation
Joint inflammations
Primary or secondary adrenocortical insufficiency
Acute adrenocortical insufficiency
Shock unresponsive to conventional therapy
Congenital adrenal hyperplasia
Hypercalcemia associated with cancer
Nonsuppurative thyroiditis
Rheumatic Disorders
Dermatologic Diseases (Allergic States
Severe seborrheic dermatitis
Severe psoriasis
Pemphigus
Severe erythema multiforme)
Control of severe or incapacitating allergic conditions (Bronchial asthma
Contact dermatitis
Atopic dermatitis
Serum sickness
Seasonal or perennial allergic rhinitis
Drug hypersensitivity reactions
Urticarial transfusion reactions
Acute noninfectious laryngeal edema)
Ophthalmic Diseases (Herpes zoster ophthalmicus
Iritis
iridocyclitis
Chorioretinitis
Diffuse posterior uveitis and choroiditis
Optic neuritis)
Gastrointestinal Diseases
Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy
Loeffler's syndrome
Aspiration pneumonitis
Hematologic Disorders (Acquired
autoimmune hemolytic anemia
Idiopathic thrombocytopenic purpura in adults
Secondary thrombocytopenia
Erythroblastopenia)
Neoplastic Diseases (Leukemias and lymphomas in adults
Acute leukemia of childhood)
Edematous States
Acute exacerbations of multiple sclerosis

Precaution

CHF, hypertension, DM, epilepsy, elderly, patients on prolonged therapy. Gradual withdrawal, pregnancy and lactation. Lactation: Drug enters breast milk; use with caution

Side Effects

Sodium and fluid retention. Potassium and calcium depletion. Muscle wasting
weakness
osteoporosis. GI disturbances and bleeding. Increased appetite and delayed wound healing. Bruising
striae
hirsutism
acne
flushing. Raised intracranial pressure
headache
depression
psychosis
menstrual irregularities. Hyperglycaemia
glycosuria
DM
obesity
moon-face
buffalo hump. Suppression of pituitary-adrenocortical system. Growth retardation in childn (prolonged therapy). Increased susceptibility for infection. Topical use: Dermal atrophy
local irritation
folliculitis
hypertrichosis. Inhaled corticosteroids: May cause hoarseness
candidiasis of mouth and throat. Topical application to the eye: Can produce corneal ulcers
raised IOP and reduced visual function. Intralesional injection: Local hypopigmentation of deeply pigmented skin. Intra-articular injection: Joint damage
fibrosis esp in load bearing joints. Potentially Fatal: Abrupt withdrawal leading to acute adrenal insufficiency. Rapid IV Inj may cause CV collapse.

Contra indication

Viral/fungal infections, tubercular or syphilitic lesions, bacterial infections unless used in conjunction with appropriate chemotherapy.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Thiazides may enhance hyperglycaemia and hypokalaemia caused by corticosteroids. Increased incidence of peptic ulcer or GI bleeding with concurrent NSAIDs admin. Response to anticoagulants altered. Dose of antidiabetics and antihypertensives needs to be increased. Decreases serum conc of salicylates and antimuscarinic agents. Ethanol may enhance gastric mucosal irritation. Reduced efficacy with concurrent use of carbamazepine, phenytoin, primidone, barbiturates and rifampicin. Mutual inhibition of metabolism between ciclosporin and corticosteroids increase plasma conc of both drugs. Enhanced effect in women taking oestrogens or oral contraceptives.