Active Substance: Noradrenaline (as tartrate).
Overview
Welcome to Dwaey, specifically on NORADRENALINE (Base) AGUETTANT 1mg/ml page.
This medicine contains an important and useful components, as it consists of
Noradrenaline (as tartrate)is available in the market in concentration
Norepinephrine (Noradrenaline)
Not a substitute for replacement of blood, plasma, fluids, and/or electrolytes; correct volume depletion prior to admin. Identify and correct hypoxia, hypercapnia and acidosis prior to or during admin. Avoid extravasation as tissue necrosis may occur. Avoid inj into leg veins, especially in elderly or those with occlusive vascular diseases, arteriosclerosis, DM or Buerger's disease. Hypertensive or hyperthyroid patients. In conjunction with local anaesthetics, do not use in fingers, toes, ears, nose or genitalia. Lactation. Lactation: Not known if excreted into breast milk; avoid use during breastfeeding
Acute Hypotension, Cardiac Arrest, Sepsis & Septic Shock
Hypersensitivity. Hypertension. Pregnancy. Patients with peripheral or mesenteric vascular thrombosis unless necessary as a life-saving procedure. Concomitant use with some general anesthetics: Chloroform, trichloroethylene, cyclopropane, halothane
Hypertension, headache, peripheral ischaemia, bradycardia, arrhythmias, anxiety, skin necrosis (with extravasation), dyspnoea, respiratory difficulty.
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Norepinephrine is a direct-acting sympathomimetic which stimulates alpha 1- and beta-adrenergic receptors. Its alpha-agonist effects cause vasoconstriction, thereby raising systolic and diastolic BP with reflex slowing of heart rate.
Guanethidine, methyldopa, reserpine, TCAs may increase pressor response to norepinephrine. Potentially Fatal: Increased risk of arrhythmias with cocaine, cyclopropane or halogenated hydrocarbon anaesthetics. Hypertensive crisis may occur with MAOIs. Hypertensive effects may be increased by nonselective ?-blockers.
Information not available