NEUTRALCA-S Price in UAE

Overview

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This medicine contains an important and useful components, as it consists of
Aluminium OH, Magnesium OHis available in the market in concentration

Name

Aluminium Hydroxide + Magnesium Hydroxide

Precaution

Chronic renal impairment; CHF; oedema; cirrhosis and low Na diets; patients with recent GI haemorrhage. Administer 2-3 hrs before/after another medication to minimise drug interactions. Pregnancy and lactation. Lactation: excretion in milk unknown; use caution

Indication

Heartburn, Reflux oesophagitis, Hyperacidity, Peptic ulcer, Constipation, Indigestion

Contra indication

Hypersensitivity to aluminium salts.

Side Effect

>10% Aluminum oxide,Chalky taste,Constipation,Fecal impaction,Stomach cramps Frequency Not Defined Aluminum oxide,Nausea,Vomiting,Aluminum intoxication,Hypophosphatemia,Osteomalacia,Magnesium oxide,Diarrhea,Hypermagnesemia

Pregnancy Category ID

Mode of Action

Alumunium hydroxide acts on the HCl in the stomach by neutralization, forming aluminium chloride salt and water. Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.

Interaction

Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine. Magnesium Hydroxide: Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.