Active Substance: Carbimazole.
Overview
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This medicine contains an important and useful components, as it consists of
Carbimazoleis available in the market in concentration
Carbimazole
Liver diseases, pregnancy, lactation.
Grave's disease, Hyperthyroidism, Diabetic nephropathy, Preparation for thyroidectomy
Hyperthyroidism due to nodular goitre.
Mild leucopaenia, sore throat, mouth ulcers, fever, bruising, malaise; rarely cholestatic jaundice; nephrotic syndrome. Nausea, loss of taste, headache, arthralgia, alopoecia. Potentially Fatal: Agranulocytosis, aplastic anaemia, hypoprothrombinaemia, neutropaenia; hypothyroidism and goitre.
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Carbimazole is metabolised to methimazole which is responsible for its antithyroid action. It blocks the production of thyroid hormones by inhibiting thyroid peroxidase.
Increased serum levels of theophylline or may develop toxicity. May enhance the effect of anticoagulants. Potentially Fatal: Increased sensitivity to warfarin in hyperthyroidism and careful control required as patient is rendered euthyroid.
Information not available