MIRCERA 50mcg/0.3ml Price
Active Substance: Methoxy polyethylene glycol-epoetin beta (Pegzerepoitin alfa).
Overview
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This medicine contains an important and useful components, as it consists of
Methoxy polyethylene glycol-epoetin beta (Pegzerepoitin alfa)is available in the market in concentration
Name
Methoxy Polyethyelene Glycol-Epoetin Beta
Precaution
Discontinue if pure red cell aplasia. Adequate control of BP. Hemoglobinopathies, seizures, platelet level >500 x 109/L. Patients <18 yr. Lactation: not known if excreted in breast milk, use caution
Indication
Anaemia associated with chronic kidney disease
Contra indication
Hypersensitivity. Uncontrolled HTN.
Side Effect
>10% Hypertension (13%),Diarrhea (11%),Nasopharyngitis (11%) 1-10% Headache (9%),Upper respiratory tract infection (9%),Cough (6%),Hypotension (5%),Urinary tract infection (5%),Procedural arteriovenous fistula thrombosis (5%) Frequency Not Defined Coronary artery disease,Anemia,Septic shock,Serious cardiovascular and thromboembolic events,Seizures,Immunogenicity related PRCA,Increased mortality and/or tumor progression in cancer patients,Increased mortality,Concomitant termination of other CRF therapy,Stevens-Johnson syndrome,Toxic epidermal necrolysis
Pregnancy Category ID
3
Mode of Action
Methoxy Polyethyelene Glycol-Epoetin Beta is an erythropoietin receptor activator w/ greater activity as well as increased half-life, in contrast to erythropoietin.
Interaction
No interaction studies have been performed. There is no evidence that Mircera alters the metabolism of other medicinal products.
Pregnancy Category Note
Information not available
Adult Dose
Child Dose
Renal Dose
Administration
