Active Substance: Meloxicam.
Overview
Welcome to Dwaey, specifically on MELOFAST 7.5mg page.
This medicine contains an important and useful components, as it consists of
Meloxicamis available in the market in concentration
Meloxicam
History of GI disease, asthma, hypertension, CVD or risk factors, fluid retention or heart failure. Monitor patients with advanced renal disease. May impair ability to drive or operate machinery. Elderly. Pregnancy (avoid in the 3rd trimester) and lactation.
Rheumatoid arthritis, Osteoarthritis, Ankylosing spondylitis
Hypersensitivity to meloxicam, aspirin or other NSAIDs; severe hepatic impairment; bleeding disorders; renal failure without dialysis. Rectal admin in patients with proctitis, haemorrhoids or rectal bleeding.
1-10% Indigestion (3.8-9.5%),Upper respiratory infection (<8.3%),Headache (2.4-8.3%),Diarrhea (1.9-7.8%),Nausea (2.4-7.2%),Abdominal pain (1.9-4.7%),Edema (0.6-4.5%),Anemia (<4.1%),Dizziness (1.1-3.8%),Constipation (0.8-2.6%),Angina (<2%),Congestive heart failure (<2%),Decreased platelet aggregation, purpuric disorder (<2%),Gastrointestinal (GI) hemorrhage (<2%),GI perforation, GI ulcer (<2%),Hepatitis (<2%),Hypertension (<2%),Inflammatory disorder of digestive tract (<2%),Myocardial infarction (<2%),Vomiting (<3%) <1% Anaphylactoid reaction,Angioedema,Fever,Asthma, bronchospasm,Cerebrovascular accident,Erythema multiforme, erythroderma,Immune hypersensitivity reaction,Interstitial nephritis, renal failure,Jaundice, liver failure,Stevens-Johnson syndrome,Tinnitus, hearing loss,Toxic epidermal necrolysis Potentially Fatal: Stevens Johnson syndrome, thrombocytopenia, interstitial nephritis and idiosyncratic liver abnormality.
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Meloxicam is an oxicam derivative which exhibits analgesic, antipyretic and anti-inflammatory actions. It reversibly inhibits the cyclooxygenase-1 and -2 (COX-1 and -2) enzymes, thus resulting in reduced synthesis of prostaglandin precursors.
Increased risk of severe GI effects w/ aspirin or warfarin. May antagonise antihypertensive effects of ACE inhibitors and angiotensin II receptor antagonists. May reduce natriuretic effects of furosemide and thiazides. Enhanced toxicity of methotrexate. May increase plasma lithium concentration.
Pregnancy category: C; D in third trimester of pregnancy; drug should be avoided in late pregnancy