LORIC 100 price in UAE

Overview

Welcome to Dwaey, specifically on LORIC 100 Tablets page.
This medicine contains an important and useful components, as it consists of Allopurinol.
LORIC 100 is available in the market in concentration 100mg/Tablet and in the form of Tablets.

OMAN PHARMACEUTICAL PRODUCTS is the producer of LORIC 100 and it is imported from OMAN, The most popular alternatives of LORIC 100 are listed downward .

Mode Of Action

Allopurinol is an inhibitor of the enzyme xanthine oxidase which converts hypoxanthine to xanthine then uric acid. The reduced production of uric acid relieves all symptoms associated with hyperuricaemia and gout. Inhibition of xanthine oxidase leads to accumulation of its substrates hypoxanthine and xanthine but since their renal clearance is more than 10 times that of uric acid, there is no risk of nephrolithiasis.

Indication

Hyperuricaemia
Uric acid nephropathy
Cancer therapy-induced hyperuricaemia
Gout
Recurrent renal stones

Precaution

Ensure adequate fluid intake. Prophylactically with an anti-inflammatory or colchicine for at least 1 mth. Withdraw immediately when sensitivity (skin rash, etc) appears. Pregnancy, lactation. Hepatic and renal impairment. Lactation: Agent is distributed into breast milk; use with caution.

Side Effects

1-10% Rash (1.5%)
Nausea (1.3%)
Renal failure (1.2%)
Vomiting (1.2%) Frequency Not Defined Amblyopia
Arthralgias
Blood dyscrasias
Bronchospasm
Cardiovascular abnormalities
Cataracts
Confusion
Decrease in libido
Dizziness
Ecchymosis
Electrolyte abnormalities
Epistaxis
Foot drop
Hematuria
Hepatotoxicity
Hypotonia
Iritis
Kidney function abnormality
Macular retinitis
Malaise
Neuritis
Pharyngitis
Pruritus
Skin edema
Stevens-Johnson syndrome
Sweating
Tinnitus Potentially Fatal: Stevens-Jonhson and/or Lyell's Syndrome (urticaria
fever
lymphadenopathy
arthralgia). Occasionally
thrombocytopaenia
agranulocytosis and aplastic anaemia.

Contra indication

Hypersensitivity; acute attack of gout.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

May inhibit the metabolism of mercaptopurine and azathioprine; reduce dose of mercaptopurine and azathioprine when given w/ allopurinol. May increase effect of warfarin and other coumarin anticoagulants. Increased excretion of the oxipurinol (metabolite) w/ salicylates or uricosuric agents. Increased toxicity w/ thiazide diuretics, some antibacterials, other antineoplastics, ciclosporin, some sulfonylurea antidiabetics, theophylline and vidarabine.