LOPRESOR 100mg price in UAE

Overview

Welcome to Dwaey, specifically on LOPRESOR 100mg Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Metoprolol.
LOPRESOR 100mg is available in the market in concentration 100mg/Tablet and in the form of Tablets/Film-coated.

NOVARTIS PHARMA AG is the producer of LOPRESOR 100mg and it is imported from SWITZERLAND, The most popular alternatives of LOPRESOR 100mg are listed downward .

Mode Of Action

Metoprolol selectively inhibits beta1-adrenergic receptors but has little or no effect on beta2-receptors except in high doses. It does not exhibit membrane stabilising or intrinsic sympathomimetic activity.

Indication

Heart failure
Migraine
Acute MI
Diabetic nephropathy
Hypertension
Cardiac arrhythmias
Angina pectoris

Precaution

Patients w/ myasthenia gravis, well-compensated heart failure, bronchospastic disease, AV conduction disorders, substantial cardiomegaly. May mask signs and symptoms of hyperthyroidism and hypoglycaemia. Patients w/ history of cardiac failure or those w/ minimal cardiac reserve. Patients undergoing major surgery involving general anaesth. Avoid abrupt withdrawal as it may precipitate thyroid storm or MI, and may exacerbate angina and ventricular arrhythmias. Hepatic impairment. Pregnancy and lactation. Patient Counselling May affect ability to drive or operate machinery. Monitoring Parameters Monitor BP, ECG and heart rate. Lactation: Drug is concentrated in breast milk; use with caution (American Academy of Pediatrics states that drug is compatible with nursing)

Side Effects

1-10% Dizziness (10%)
Headache (10%)
Tiredness (10%)
Depression (5%)
Diarrhea (5%)
.Pruritus (5%)
Bradycardia (9%)
Rash (5%)
Dyspnea (1-3%)
Cold extremities (1%)
Constipation (1%)
Dyspepsia (1%)
Heart failure (1%)
Hypotension (1%)
Nausea (1%)
Flatulence (1%)
Heartburn (1%)
Xerostomia (1%)
Wheezing (1%)
Bronchospasm (1%) Frequency Not Defined Decreased exercise tolerance
Raynaud phenomenon
Increased triglyceride levels and insulin resistance
decreased high-density lipoprotein (HDL) levels

Contra indication

2nd or 3rd degree AV block, sick sinus syndrome, hypotension, decompensated heart failure, sinus bradycardia, severe peripheral arterial circulatory disorders, cardiogenic shock, severe asthma and bronchospasm, untreated phaeochromocytoma, Prinzmetal's angina, metabolic acidosis.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Additive effect w/ catecholamine-depleting drugs (e.g. reserpine) and MAOIs. May antagonise ?1-adrenergic stimulating effects of sympathomimetics. Additive negative effects on SA or AV nodal conduction w/ cardiac glycosides, nondihydropyridine Ca channel blockers. Paradoxical response to epinephrine may occur. Increased plasma concentrations w/ CYP2D6 inhibitors (e.g. bupropion, cimetidine). Increased risk of hypotension and heart failure w/ myocardial depressant general anaesth (e.g. diethyl ether). Risk of pulmonary HTN w/ vasodilators (e.g. hydralazine) in uraemic patients. Reduced plasma levels w/ rifampicin. May increase negative inotropic and negative dromotropic effect of antiarrhythmic drugs (e.g. quinidine, amiodarone). May reduce antihypertensive efficacy w/ indometacin. May increase effects of hypoglycaemics.