LIDOCAINE 5% Price

Overview

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This medicine contains an important and useful components, as it consists of
Lidocaine Baseis available in the market in concentration

Name

Lidocaine Hydrochloride

Precaution

Hepatic or renal impairment; CHF and following cardiac surgery; bradycardia; respiratory depression; porphyria; elderly or debilitated patients; pregnancy. Lactation: crosses into breast milk, use caution

Indication

Ventricular arrhythmias, Haemorrhoids, Sympathetic nerve block, Peripheral nerve block, Perianal pain and itching, Ventricular fibrillation or ventricular tachycardia, Epidural anaesthesia, Spinal anaesthesia, Regional anaesthesia, Surface anaesthesia, Pupil dilatation

Contra indication

Hypovolaemia; heart block or other conduction disturbances.

Side Effect

Common Cardiovascular: Hypotension Dermatologic: Edema, erythema at injection site, petechiae, skin irritation Gastrointestinal: Constipation, Nausea, vomiting Neurologic: Confusion, dizziness, headache, paresthesia, somnolence, tremor Other: Irritation symptom, Topical products; ie, erythema, edema Serious Cardiovascular: Cardiac arrest, cardiac dysrhythmia Hematologic: Methemoglobinemia Neurologic: Seizure Anaphylactoid reactions Malignant hyperthermia Potentially Fatal: Hypotension and bradycardia leading to cardiac arrest; anaphylaxis.

Pregnancy Category ID

2

Mode of Action

Lidocaine is an amide type local anaesth. It stabilises the neuronal membrane and inhibits Na ion movements, which are necessary for conduction of impulses. In the heart, lidocaine reduces depolarisation of the ventricles during diastole and automaticity in the His-Purkinje system. Duration of action potential and effective refractory period are also reduced.

Interaction

May increase serum levels w/ cimetidine and propranolol. Increased risk of cardiac depression w/ ?-blockers and other antiarrhythmics. Additive cardiac effects w/ IV phenytoin. Hypokalaemia caused by acetazolamide, loop diuretics and thiazides may antagonise effect of lidocaine. Dose requirements may be increased w/ long-term use of phenytoin and other enzyme-inducers.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration