LEVOFLOX 500 price in UAE

Overview

Welcome to Dwaey, specifically on LEVOFLOX 500 Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Levofloxacin.
LEVOFLOX 500 is available in the market in concentration 500mg/Tablet and in the form of Tablets/Film-coated.

NATIONAL PHARMACEUTICAL INDUSTRIES CO. (SAOG) is the producer of LEVOFLOX 500 and it is imported from OMAN, The most popular alternatives of LEVOFLOX 500 are listed downward .

Mode Of Action

Levofloxacin exerts antibacterial action by inhibiting bacterial topoisomerase IV and DNA gyrase, the enzymes required for DNA replication, transcription repair and recombination. It has in vitro activity against a wide range of gram-negative and gram-positive microorganisms.

Indication

Chronic bronchitis
Acute bacterial sinusitis
Anthrax
Community-acquired pneumonia
Skin and skin structure infections
Nosocomial pneumonia
Urinary tract infections
Complicated skin and skin structure infections
Acute pyelonephritis
Chronic bacterial prostatitis

Precaution

Known or suspected CNS disorders (e.g. severe cerebral arteriosclerosis, epilepsy) or other risk factors that predispose to seizures. Avoid unnecessary exposure to sunlight or artificial UV light. History of prolonged QT interval, uncorrected electrolyte disturbances. DM (carefully monitor blood glucose levels). Periodically monitor renal, hepatic and haematopoietic functions during treatment. Pregnancy and lactation. Elderly. May impair ability to drive or operate machinery. Lactation: Drug excreted in breast milk; not recommended

Side Effects

1-10% Nausea (7%)
Headache (6%)
Diarrhea (5%)
Insomnia (4%)
Constipation (3%)
Dizziness (3%)
Dyspepsia (2%)
Rash (2%)
Vomiting (2%)
Chest pain (1%)
Dyspnea (1%)
Edema (1%)
Fatigue (1%)
Injection-site reaction (1%)
Moniliasis (1%)
Pain (1%)
Pruritus (1%)
Vaginitis (1%) <1% Cardiac: Cardiac arrest
palpitation
ventricular tachycardia
arrhythmia Nervous system: Tremor
convulsions
paresthesia
vertigo
hypertonia
hyperkinesias
abnormal gait
somnolence
syncope Metabolic: Hypoglycemia
hyperglycemia
hyperkalemia Blood/lymphatic system: Anemia
thrombocytopenia
granulocytopenia Musculoskeletal/connective tissue: Arthralgia
tendonitis
myalgia
skeletal pain Gastrointestinal (GI): Gastritis
stomatitis
pancreatitis
esophagitis
gastroenteritis
glossitis
pseudomembranous/C difficile colitis Hepatobiliary: Abnormal hepatic function
increased hepatic enzymes
increased alkaline phosphatase Psychiatric: Anxiety
agitation
confusion
depression
hallucinations
nightmares
sleep disorder
anorexia
abnormal dreaming Other: Immune hypersensitivity reaction
acute renal failure
urticaria
phlebitis
epistaxis Potentially Fatal: Anaphylaxis.

Contra indication

Hypersensitivity to levofloxacin or other quinolones. Child <18 yr.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Additive effects on QT interval prolongation w/ class IA (e.g. quinidine, procainamide) or class III (amiodarone, sotalol) antiarrhythmics, fluoxetine or imipramine. Reduced absorption w/ sucralfate, didanosine, antacids containing Mg or Al, dietary supplements containing Zn, Ca, Mg or Fe. Altered glucose levels w/ antidiabetic agents (e.g. insulin, glibenclamide). Increased risk of severe tendon disorders w/ corticosteroids. Increased risk of CNS stimulation and seizures w/ NSAIDs. Increased prothrombin time w/ warfarin.