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LEUKERAN 2mg Price

Active Substance: Chlorambucil.

343
UAD , based on 7541 reviews.
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Overview

Welcome to Dwaey, specifically on LEUKERAN 2mg page.
This medicine contains an important and useful components, as it consists of
Chlorambucilis available in the market in concentration

Name

Chlorambucil

Precaution

Renal or hepatic dysfunction. Perform blood counts regularly. Seizure disorder, bone marrow suppression. Patient who has received radiation therapy, myelosuppressive drugs or has a depressed baseline leukocyte/platelet count within the previous 4 wk. Increased incidence of acute leukaemias and other secondary malignancies. Lactation: not known if excreted in breast milk; do not nurse

Indication

Lymphocytic leukemia, non-Hodgkin lymphoma, Waldenstrm macroglobulinemia, polycythemia vera, trophoblastic neoplasms, ovarian carcinoma, nephrotic syndrome, Hodgkin's disease

Contra indication

Hypersensitivity. Pregnancy and lactation. Porphyria.

Side Effect

>10% Neutropenia (25-33%),Anemia,Leukopenia,Thrombocytopenia Frequency Not Defined Seizures,Hallucinations,Peripheral neuropathy,Nausea,Vomiting,Pulmonary fibrosis,GI effects,Leukemia,Myelosuppression,Hyperuricemia,Infertility,Hepatotoxicity & jaundice,Type I hypersensitivity,Rash,Stevens-Johnson syndrome (rare),Toxic epidermal necrosis (rare),Urticaria,Erythema multiforme (rare),Secondary malignancies Potentially Fatal: Severe bone marrow suppression, carcinogenic and human infertility.

Pregnancy Category ID

4

Mode of Action

Chlorambucil interferes with DNA replication and RNA transcription by alkylation and cross-linking cellular DNA strands, thus leading to disruption of the nucleic acid function.

Interaction

Impairs immune response to vaccines, possible infection after admin of live vaccines.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration

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