LEUKERAN 2mg Price

Overview

Welcome to Dwaey, specifically on LEUKERAN 2mg Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Chlorambucil.
LEUKERAN 2mg is available in the market in concentration 2mg/Tablet and in the form of Tablets/Film-coated.

EXCELLA GmbH is the producer of LEUKERAN 2mg and it is imported from GERMANY, The most popular alternatives of LEUKERAN 2mg are listed downward .

Mode Of Action

Chlorambucil interferes with DNA replication and RNA transcription by alkylation and cross-linking cellular DNA strands, thus leading to disruption of the nucleic acid function.

Indication

• Lymphocytic leukemia
• non-Hodgkin lymphoma
• Waldenstrm macroglobulinemia
• polycythemia vera
• trophoblastic neoplasms
• ovarian carcinoma
• nephrotic syndrome
• Hodgkin's disease

Precaution

Renal or hepatic dysfunction. Perform blood counts regularly. Seizure disorder, bone marrow suppression. Patient who has received radiation therapy, myelosuppressive drugs or has a depressed baseline leukocyte/platelet count within the previous 4 wk. Increased incidence of acute leukaemias and other secondary malignancies. Lactation: not known if excreted in breast milk; do not nurse

Side Effects

• >10% Neutropenia (25-33%)
• Anemia
• Leukopenia
• Thrombocytopenia Frequency Not Defined Seizures
• Hallucinations
• Peripheral neuropathy
• Nausea
• Vomiting
• Pulmonary fibrosis
• GI effects
• Leukemia
• Myelosuppression
• Hyperuricemia
• Infertility
• Hepatotoxicity & jaundice
• Type I hypersensitivity
• Rash
• Stevens-Johnson syndrome (rare)
• Toxic epidermal necrosis (rare)
• Urticaria
• Erythema multiforme (rare)
• Secondary malignancies Potentially Fatal: Severe bone marrow suppression
• carcinogenic and human infertility.

Contra indication

Hypersensitivity. Pregnancy and lactation. Porphyria.

Pregnancy and lactation

Pregnancy category: D

There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.